Podophyllum

Podophyllum is used as a caustic for removal of warts, calluses and papillomas etc. It was formerly used as a cathartic.


Brands
Adult Dose
Dose: 0.15 to 0.3 %
Single Dose: 0.22 (0.225)
Frequency: As recommended.
Route: Topical
Instructions: As Required
Neonatal
Dose: 15 to 30 %
Single Dose: 22 (22.5)
Frequency: As recommended.
Route: Topical
Instructions: As Required
Paedriatic
Dose: 15 to 30 %
Single Dose: 22 (22.5)
Frequency: As recommended.
Route: Topical
Instructions: As Required
Characteristics
. It is of Natural origin and belongs to Alkaloid. It belongs to Dermatological-Caustic pharmacological group on the basis of mechanism of action and also classified in Dermatological Products pharmacological group.The Molecular Weight of Podophyllum is 414.40.
Contraindications
Podophyllum is contraindicated in conditions like Haemorrhage,Friable warts.
Effects
The severe or irreversible adverse effects of Podophyllum, which give rise to further complications include Vomiting, Diarrhoea, Neuropathy, Confusion, Delirium, Paralytic ileus, Abdominal pain, Leucopenia, Coma, Lethargy.The signs and symptoms that are produced after the acute overdosage of Podophyllum include Diarrhea, Abdominal pain, Nausea & vomiting, Neuropathy, Bone marrow suppression.The symptomatic adverse reactions produced by Podophyllum are more or less tolerable and if they become severe, they can be treated symptomatically, these include Pain, Allergy, Swelling.
Indications
Podophyllum is primarily indicated in conditions like Warts.
Interactions
No data regarding the interactions of Podophyllum was found.
Interfrence
Risks
Drug should not be given to Paediatrics, Pregnant Mothers, and Neonates.If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.
Storage
Solution,Cream,Ointment Store in a well closed container, Below 40°C. Protect from Sunlight.
Warnings
Podophyllum should not be used during pregnancy or lactation or to children. Avoid prolonged or excessive use.
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