Pizotifen (Hydrogen Maleate)

Pizotifen (Hydrogen Maleate) used for the prevention of migraine.


Adult Dose
Dose: 0.5 mg
Single Dose: 0.5 (0.5)
Frequency: 8 hourly
Route: PO
Instructions: Maintenance dose,
Neonatal
Paedriatic
Dose: 0.02 mg/kg
Single Dose: 0.02 (0.02)
Frequency: 8 hourly
Route: Oral
Instructions: Dose for Children of 5-12 Yrs
Characteristics
. It is of Synthetic origin and belongs to Piperidine. It belongs to 5HT-2 antagonist pharmacological group on the basis of mechanism of action and also classified in Psychotherapeutic Drugs and Appetite Stimulant pharmacological group.The Molecular Weight of Pizotifen (Hydrogen Maleate) is 429.50. Its pKa is 8.7.
Contraindications
Pizotifen (Hydrogen Maleate) is contraindicated in conditions like Glucoma,Prostatic hypertrophy.
Effects
The symptomatic adverse reactions produced by Pizotifen (Hydrogen Maleate) are more or less tolerable and if they become severe, they can be treated symptomatically, these include Dizziness, Drowsiness, Dry mouth, Increased appetite.
Indications
Pizotifen (Hydrogen Maleate) is primarily indicated in conditions like Appetite stimulation, Migraine prophylaxis, Prevention of vascular headache, Prophylaxis of vascular headache.
Interactions
No data regarding the interactions of Pizotifen (Hydrogen Maleate) was found.
Interfrence
Risks
Drug should not be given to Pregnant Mothers, and Neonates.If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.
Storage
Tab, Elixir
Warnings
Patients should be warned that owing to its possible sedative effect, pizotifine may slow their reactions when driving vehicles or operating machinery etc.
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