PYRICAM PYRICAM ORAM ORAM ORAM ORAM MEDROX BREXIN RHEUCAM RHEUCAM RHEUCAM RHEUCAM CALIMENT CALIMENT CALIMENT CALIMENT GLOXI ZICAM ZICAM PAXYL RUPIROX ABXICAM ABXICAM PIROXIM PIROXIM PIROXIM SOCALM ROSIDEN ROSIDEN ROSIDEN ROSIDEN ROSIDEN PCAM PCAM PCAM PCAM PCAM PCAM TRAUMALAX TRAUMALAX PROXIM PROXIM PROXIM LOCAM DIODEX DIODEX DIODEX FELDENE FELDENE FELDENE FELDENE FELDENE FELDENE FELDENE FFD ZERAX ROXIDIN ROXIDIN ROXIDIN PIROX ARCAM LIMBAR LIMBAR RUMOLON RUMOLON RUMOLON RUMOLON RUMOLON ROXICAM ROXICAM ROXICAM AKSOCAM AKSOCAM PIROC BRUXICAM INDENE FEDRACAM FEDRACAM FEDRACAM FOSTER FOSTER PAYARAM DELPROX MOBICAM MOBICAM MOBICAM DISCAM DISCAM CAP-20 SANDAN DISPERSIBLE SANDAN DISPERSIBLE GEL-CAM XYCAM XYCAM PIRO-D ERICAM ERICAM TASOCAM FELOXICAM SWATCH PELCAM OSTEOCAM OSTEOCAM PAXAM SYNTEC PIROFLAM FYCAM FYCAM ROXIC TACTIC UTRAHIT PALADON VOLIKA NALDENE AXICAM FELCAM FELCAM RUMOLON INJ RIACEN PRECAM-20 CYCLODEX DELPIROX PIRAM PIRAM FAI-CAM FELDICAM FELDICAM INFAREL ORTHRAM RAPICAM RHEUMONIL VASCAM VINCAM WELDENE WELDENE FENOXIM COMATIC MUVON INFLAROX OXICAM OXICAM OXICAM OXICAM PHELODENE SALDEN ALOXIN ROCICIAN ALLICAM ALLICAM FROGEN PROXILIB O-ZOLE O-ZOLE INFLACID COMFAM RIPOCAM SONICAM OXIBET PROPAIN ANAROM ANAROM PHAROX PHAROX PHAROX PIRODEX PIROSIL PULSECAM PULSECAM SIMROXY FELAXICAM CYCLODOR XEGEN EXICAN EXICAN EXICAN HOCAM JALDIN MCDEX MOD MOD MODIVID MODIVID NOVAGESIC PANCARE PIROTEK PIROTEL PIROTEL PIROXICAM PIROXICAM ICAM CYDEX ROCICAIN ROCICAIN BIOCAM BIOCAM BIOCAM DAVIROX BRYSK TROST TROST BLESS BROVEN BROVEN BROZICAM BROZICAM VIEPRAM EPHAROX EPHAROX POXICAM POXICAM POXICAM PIROBET OXIPRO OXIPRO PIROFEL PIROFEL ALICAM HYALGAN GEL CAMGEN CAMGEN MARICAM TRIX BETADEX RHEUPAIN RHEUPAIN AMOLIVE ARSICAM BEKA BETAMARK BIODEXTRIN BROKSIN BROPOX CAM CAM CYCLOBEX EVER-PIR FAPRO FASICAMX MREXIN OXYCLOD PAINLES PAYRAM PERDIN PHAROX-B PIRICAM PIROJOINT PIROLIVE PIROMIN PIROXIBET PIROXIBRON PIROXIROWN-B PRECAM PREKSIN PYROCAM PYROXI QITAR RHEUMATUS RHEUMATUS ROXBEX ROXIC SPONAC TASOCAM-B CYCLOCAM PLUS EXICAN B MOBICAMT MQUIN PIROXILITE RIACEN RIACEN RIACEN CAMITLE CIRER DEXIN HELDENE PAIN-R PERICAM PIRAXIN PIROWAN PIXICAM ROXSY SICAM STAPIROX TEXTRIN XORIP ZECAM ROXIM BREXA NICEP NICEP BCD-20 PAXIL 20 ORTHOSAP ORTHOSAP BELADEX BETANE NAGID PARQIN QLUZ WELCAME

Dose: 20 mg
Single Dose: 20 (20)
Frequency: 24 hourly
Route: PO
Instructions: Maintenance for 1-2 Weeks

Dose:
Single Dose:
Frequency:
Route:
Instructions: Not recommended in this age group

Dose:
Single Dose:
Frequency:
Route:
Instructions: Not recommended in this age group

. It is of Synthetic origin and belongs to Oxicam. It belongs to Cyclo-oxygenase inhibitor pharmacological group on the basis of mechanism of action and also classified in Analgesics and Anti-inflammatory Agents pharmacological group.The Molecular Weight of Piroxicam is 331.30. Its pKa is 6.3.

Piroxicam is contraindicated in conditions like Peptic ulcer,Thrombosis,Impaired hepatic function.

The severe or irreversible adverse effects of Piroxicam, which give rise to further complications include Skin reactions, Erythema.Piroxicam produces potentially life-threatening effects which include GI bleeding, Aplastic Anemia, Renal damage, Peptic ulceration, Purpura, Pemphigus vulagris. which are responsible for the discontinuation of Piroxicam therapy.The signs and symptoms that are produced after the acute overdosage of Piroxicam include Nausea, Vomiting, Diarrhea, Hematuria, GI disturbances, Renal failure, GI hemorrhage, Proteinuria, Hypoprothrombinemia.The symptomatic adverse reactions produced by Piroxicam are more or less tolerable and if they become severe, they can be treated symptomatically, these include Dizziness, Headache, Palpitation, Insomnia, Confusion, VertigoX, Hearing loss, Mood swings, Paresthesias, Hypoglycemia.

Piroxicam is primarily indicated in conditions like Acute gout, Acute spasm and spasm in diagnostic procedures, Ankylosing spondylitis, Benign gastric and duodenal ulceration, Duodenal ulceration, Gout, Juvenile chronic arthritis, Musculoskeletal disorders, Nausea and vomiting (palliative care), Osteoarthritis, Pain, Resistant oedema, Rheumatoid arthritis.

Piroxicam is known to interact with other drugs, the details of drug interactions is as follows:DrugDetailsSeverityOnsetManagementAspirinCombined use of aspirin with piroxicam aggravate gastrointestinal toxicity. aspirin at higher doses decrease the plasma concentration of piroxicam. ADVICE: Avoid concomitant use of Aspirin with NSAIDs (increased risk of side effects). ModerateDuring concomitant therapy, patient should take medication with food and should immediately report to physician about sign and symptoms of GI ulceration and bleeding.BenorylateCholine Magnesium TrisalicylateCimetidine (HCl)MetipranololLikely interaction of PIROXICAM reducing the HYPOTENSIVE effect of METIPRANOLOL [EYE]. ModerateTorasemidePiroxicam, a strong CYP2C9 inhibitor, may increase the serum concentration of Torasemide, a CYP2C9 substrate, by decreasing Torasemide metabolism and clearance. Consider alternate therapy or monitor for changes in the therapeutic and adverse effects of Torasemide if Piroxicam is initiated, discontinued or dose changed.VORICONAZOLEPiroxicam may increase the serum concentration of voriconazole by decreasing its metabolism. Monitor for changes in the therapeutic and adverse effects Warfarin (Na)Piroxicam may enhance the anticoagulant effect of Warfarin.ModerateDelayedPatients receiving Warfarin should be instructed to not initiate Piroxicam without consulting his/her healthcare professional (nonacetylated salicylates might be safer alternatives). Acetaminophen is usually a good antipyretic and analgesic choice for patients taking Warfarin. Monitor for increased signs and symptoms of bleeding if Warfarin and Piroxicam are used concomitantly. These interactions are sometimes beneficial and sometimes may pose threats to life. Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.

Complete blood cell count

Drug should not be given to Pregnant Mothers, Geriatrics, and Neonates.If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.

Tab Store Below 40°C. Protect from Sunlight and Moisture.

Piroxicam should be used with caution in patients with intrinsic coagulation defects and those on anticoagulant therapy. It should be used with caution in patients with compromised cardiac function, hypertension other condition predisposing to fluid retention. It should be used with extra care in the presence of existing controlled infection. Perform periodic auditory function test during chronic therapy. Discontinue drug if skin reaction occurs.