Dose: 0.142 to 2.857 mg/kg
Single Dose: 1.5 (1.4995)
Frequency: 24 hourly
Route: PO
Instructions: -

Dose:
Single Dose:
Frequency:
Route:
Instructions: Not recommended in this age group

Pipothiazine also known as Pipotiazine. . It is of Natural origin and belongs to Pipothiazine. It belongs to D2 antagonist pharmacological group on the basis of mechanism of action and also classified in Psychotherapeutic Drugs pharmacological group.The Molecular Weight of Pipothiazine is 714.10.

Pipothiazine is contraindicated in conditions like Bone marrow depression,Coma,Narrow-angle glaucoma,CNS depression.

The severe or irreversible adverse effects of Pipothiazine, which give rise to further complications include Hemolytic anemia, Hemolytic anemia, Tardive dyskinesia, Leucopenia, Agranulocytosis, Hypothermia, Leucocytosis, Cardiovascular symptoms.Pipothiazine produces potentially life-threatening effects which include Neuroleptic Malignant Syndrome. which are responsible for the discontinuation of Pipothiazine therapy.The signs and symptoms that are produced after the acute overdosage of Pipothiazine include Extrapyramidal effects.The symptomatic adverse reactions produced by Pipothiazine are more or less tolerable and if they become severe, they can be treated symptomatically, these include Drowsiness, Constipation, Insomnia, Dry mouth, Impotence, Depression, Nasal congestion, Nightmares, Galactorrhea, Pallor.

Pipothiazine is primarily indicated in conditions like Post-operative nausea and vomiting, Psychosis.

Pipothiazine is known to interact with other drugs, the details of drug interactions is as follows:DrugDetailsSeverityOnsetManagementAlcoholVORICONAZOLEVoriconazole may increase the serum concentration of pipotiazine by decreasing its metabolism. Monitor for changes in the therapeutic and adverse effects These interactions are sometimes beneficial and sometimes may pose threats to life. Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.

Drug should not be given to Paediatrics, Pregnant Mothers, Geriatrics, and Neonates.If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.

Inj Protect from Sunlight.

Pipothiazine should be used with caution in patients exposed to extreme heat or phosphorus insecticides, patients in state of alcohol withdrawal, patients with history of peptic ulcer, allergic reactions, with renal impairment, prostatic hypertrophy. Photosensitization may occur, caution patients to take appropriate measures (e.g. wear protective clothing or sunscreen) against exposure to sunlight or UV light. Discontinue use atleast 48 hr before myelography.