Pholcodine

Pholcodine is a narcotic derivative related to codeine but having little analgesic activity. Pholcodine is mainly used for cough suppression.


Adult Dose
Dose: 5 to 10 mg
Single Dose: 7.5 (7.5)
Frequency: 8 hourly
Route: PO
Instructions:
Neonatal
Dose: 0.1 mg/kg
Single Dose: 0.1 (0.1)
Frequency: 8 hourly
Route: Oral
Instructions:
Paedriatic
Dose: 0.1 to 0.25 mg/kg
Single Dose: 0.18 (0.175)
Frequency: 8 hourly
Route: Oral
Instructions: -
Characteristics
. It is of Synthetic origin and belongs to Aminoalkylether. It belongs to OPIATE agonist pharmacological group on the basis of mechanism of action and also classified in Antitussives pharmacological group.The Molecular Weight of Pholcodine is 416.50. Its pKa is 8.0, 9.3.
Contraindications
Pholcodine
Effects
The severe or irreversible adverse effects of Pholcodine, which give rise to further complications include Epigastric distress, Biliary colic, Psychological dependence.The signs and symptoms that are produced after the acute overdosage of Pholcodine include Drowsiness, Respiratory depression, Ataxia, Restlessness.The symptomatic adverse reactions produced by Pholcodine are more or less tolerable and if they become severe, they can be treated symptomatically, these include Constipation, Nausea and vomiting.
Indications
Pholcodine is primarily indicated in conditions like Anxiety, Dry cough, and can also be given in adjunctive therapy as an alternative drug of choice in Primary ovarian cancer.
Interactions
No data regarding the interactions of Pholcodine was found.
Interfrence
Radioimmunoassay of Opiates in Urine
Risks
Drug should not be given to Pregnant Mothers, patients suffering from Kidney dysfunction, patients suffering from Liver Malfunction, and Geriatrics.If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.
Storage
Linctus Protect from Sunlight.
Warnings
Pholcodine should be used with caution in patients with any pre-existing kidney disease, heart disease, lungs disease, asthma, emphysema, high blood pressure, hyperthyroidism, diabetes, glaucoma, prostate trouble or if have any allergy. It should be used only if clearly needed during pregnancy or lactation.
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