Phenoperidine (HCl)

Phenoperidine (HCl) is a narcotic analgesic, used to relieve moderate to severe pain. Phenoperidine (HCl) is used with droperidol to produce neuroleptanalgesia (a state of consciousness with calmness allowing the patient to co-operate with surgeon).


Brands
Adult Dose
Dose: 0.028 to 0.071 mg/kg
Single Dose: 0.05 (0.0495)
Frequency: As recommended.
Route: IV
Instructions: As Required
Neonatal
Paedriatic
Characteristics
. It is of Synthetic origin and belongs to Opioid. It belongs to OPIATE agonist pharmacological group on the basis of mechanism of action and also classified in General Anesthetics and Analgesic-Narcotic pharmacological group.The Molecular Weight of Phenoperidine (HCl) is 403.90. Its pKa is 8.01.
Contraindications
Phenoperidine (HCl) is contraindicated in conditions like Renal diseases,Respiratory disease,Hepatic disease.
Effects
Phenoperidine (HCl) produces potentially life-threatening effects which include Respiratory depression, Severe Hypotension. which are responsible for the discontinuation of Phenoperidine (HCl) therapy.The signs and symptoms that are produced after the acute overdosage of Phenoperidine (HCl) include Cardiac arrest, Cyanosis.The symptomatic adverse reactions produced by Phenoperidine (HCl) are more or less tolerable and if they become severe, they can be treated symptomatically, these include Nausea, Constipation, Urinary retensionX, Bradycardia, Sedation, Itching, Muscle rigidity, Mood swings, Bad dreams.
Indications
Phenoperidine (HCl) is primarily indicated in conditions like Pain, and can also be given in adjunctive therapy as an alternative drug of choice in Anesthesia, Surgery.
Interactions
No data regarding the interactions of Phenoperidine (HCl) was found.
Interfrence
Risks
Drug should not be given to Paediatrics, Pregnant Mothers, patients suffering from Kidney dysfunction, patients suffering from Liver Malfunction, Geriatrics, and Neonates.If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.
Storage
Inj Store at room temperature.
Warnings
No data regarding the Warnings/Precuations of Phenoperidine (HCl) is available.
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