ORPHAMOL ORPHAMOL SINAXAMOL EXTRA SINAXAMOL ORASIC PARLEX GLOGESIC GLORAL GL GL HELIGESIC GENBROL IDEGESIC ORPHAGESIC ORPHAGESIC-P ANGESIC ACETOR NESGESIC SKELDRIN DOLEX DOLEX SAMEROL-N FORTE SAMEROL-N NUBEROL PLUS NUBEROL FORTE NORFLEX NORGESIC BAKAGESIC NUBEROL SIC ACETOFEN RID-ALL FORTE RID-ALL DURAGESIC ORPHINE P-ORPH P-ORPH CITROGESIC MEDIGESIC C MEDIGESIC C MEDIGESIC FORTE MEDIGESIC FORTE MEDIGESIC FORTE MEDIGESIC MEDIGESIC VENOGESIC WILGESIC PARAPHAN EXTRA CENADRIN AMBROGESIC MUSEADOL FORTE MUSEADOL ORPHADINE FLOGESIC FLEXODIN PANGESIC+C ORPHENA STARGESIC ORPHENAMOLE ORPHENALAX FLEXAR ORPHENARAX FINEGESIC BEGESIC ANOROL ANOROL ANOROL FORTE ORTHOFLEX FYGESIC PHENACIN SKAMREX NIL-GESIC GEPROL PAINCURE PAINCURE FORT ORFID NORDEN EXCEDRIN-XTRA ARIGESIC EXCEDRIN RIOGESIC GRAYGESIC LEXODIN OROZAN BANAKE GOODGESIC GOODGESIC LOGESIC PARAGESIC PANGESIC FORTE PARACEM ORPHENAMED ORPHENAMED GESICROL EROGESIC PARA

Dose: 100 mg
Single Dose: 100 (100)
Frequency: 12 hourly
Route: PO
Instructions:

Dose:
Single Dose:
Frequency:
Route:
Instructions: Not recommended in this age group

Dose: 5 to 13.33 mg/kg
Single Dose: 9.2 (9.165)
Frequency: 8 hourly
Route: Oral
Instructions:

It belongs to Cholinergic muscarinic antagonist pharmacological group on the basis of mechanism of action and also classified in Antiparkinson Agents and Muscle Relaxants pharmacological group.The Molecular Weight of Orphenadrine is 305.80. Its pKa is 9.

Orphenadrine is contraindicated in conditions like Glucoma,Peptic ulcer,Prostatic hypertrophy,Pyloric disease.

The severe or irreversible adverse effects of Orphenadrine, which give rise to further complications include Hallucinations, Confusion, Hallucinations, Blindness, Chest tightness, Itching, Breathing difficulty.Orphenadrine produces potentially life-threatening effects which include Anaphylactic shock, Preciptate angle closure, Raised Intraoccular pressure, Blindness. which are responsible for the discontinuation of Orphenadrine therapy.The signs and symptoms that are produced after the acute overdosage of Orphenadrine include Tachycardia, Coma, Seizures, Dry mouth, Respiratory depression, Hallucinations, Fever, Dilated pupils, Fainting, Shock.The symptomatic adverse reactions produced by Orphenadrine are more or less tolerable and if they become severe, they can be treated symptomatically, these include Headache, Drowsiness, Constipation, Dry mouth, Blurred vision, Confusion, Hallucination, Dry mouth, Confusion.

'Orphenadrine is primarily indicated in conditions like Dystonia, Musculoskeletal pain, Parkinsonism, Parkinson''s disease, Parkinson''s disease; drug-induced extrapyramidal symptoms, Vertigo, and can also be given in adjunctive therapy as an alternative drug of choice in Leg cramps.'

No data regarding the interactions of Orphenadrine was found.

Increased Level of Protein Bound Thyroxine

Drug should not be given to Paediatrics.If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.

Tab, Inj Store in a well closed container, Below 40°C. Protect from Sunlight, Moisture and Heat.

Orphenadrine should be used with caution in patients with cardiac arrhythmias, coronary insufficiency or tachycardia. Periodically monitor blood, urine and liver function values. It should be used with caution (if contain sulfites) in patients of asthma because may cause allergic reaction (including hives, itching, wheezing or anaphylaxis).