Oral Rehydration Salts (ORS)

Oral redyration salt is used for oral replacement of electrolytes and fluids in patient with dehydration associated with diarrohea. The main constitutes oral rehydration salt are anhydrous dextrose, sodium chloride, potassium chloride and either trisodium citrate dihydrate or sodium bicarbonate. The simple glucose electrolyte solutions can adequately rehydrate patients. Oral Rehydration Salts is one of the major therapeutic advances of this century and since 1960s it has saved the lives of millions of children. It has become the manistay of treatment for the dehydration and acidosis associated with acute infectious diarrohea.

Brands
OSMOLAR ORANGE OSMOLAR BANANA EUROSAL DURASAL RALYTE HYDROLYTE REHYDRATE KINO EFFER SALT PAEDICARE LEMON PAEDICARE SRTAW BERRY PAEDICARE ORANGE PAEDICARE GINGER DRILL PAEDICARE REGULAR PAEDICARE BANANA BABI SALT OSMOLESS PEDISAL ORS INFALYTE PEDIAWIN SAFELYTE ORS MERISOL
Adult Dose
Dose: 200 to 400 ml
Single Dose: 300 (300)
Frequency: As recommended.
Route: PO
Instructions: During 24 hrs., As required
Neonatal
Dose: 0.028 to 0.057 Litrtes/kg
Single Dose: 0.042 (0.0425)
Frequency: As recommended.
Route: Oral
Instructions: During 24 hrs., As required
Paedriatic
Dose: 0.028 to 0.057 Litrtes/kg
Single Dose: 0.042 (0.0425)
Frequency: As recommended.
Route: Oral
Instructions: During 24 hrs., As required
Characteristics
Oral Rehydration Salts (ORS) also known as ORS. . It is of Synthetic origin and belongs to Salts. It belongs to Nutrients and Vitamins pharmacological group on the basis of mechanism of action and also classified in Electrolyte Oral pharmacological group.
Contraindications
Oral Rehydration Salts (ORS) is contraindicated in conditions like Continued vomiting,Severe dehydration.
Effects
The severe or irreversible adverse effects of Oral Rehydration Salts (ORS), which give rise to further complications include Radiosensitization effect on thorax, Skin inflammation, Esophageal inflammation.Oral Rehydration Salts (ORS) produces potentially life-threatening effects which include Hyperkalemia, Hyperkalemia, Hypernatremia. which are responsible for the discontinuation of Oral Rehydration Salts (ORS) therapy.The signs and symptoms that are produced after the acute overdosage of Oral Rehydration Salts (ORS) include Severe vomiting, Mucositis, Diarrhea, Severe myelosuppression, Hyperkalemia, Hypernatremia.The symptomatic adverse reactions produced by Oral Rehydration Salts (ORS) are more or less tolerable and if they become severe, they can be treated symptomatically, these include Nausea, Vomiting, Alopecia, Diarrhea, Mucositis, Fever, Myalgia, Abdominal pain, Reaction at injection site, Alopecia.
Indications
Oral Rehydration Salts (ORS) is primarily indicated in conditions like Acute infectious diarrhoea, Dehydration, Diarrhoea, Fluid and electrolyte loss in diarrhoea, Fluid depletion, Rehydration of patient with burns.
Interactions
No data regarding the interactions of Oral Rehydration Salts (ORS) was found.
Interfrence
Bioassay procedures for determination of antibacterial drug levels.
Risks
Drug should not be given to patients suffering from Kidney dysfunction, and Neonates.If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.
Storage
Solution, Syrup, Powder Store in a well closed container, at room temperature.
Warnings
Use with caution in patients with pre-existing blood disorders, gout, dental disease, liver disease or heart disease. This medication is classified as pregnancy category C and should be used during pregnancy or lactation only if clearly needed. These are not appropiate for patients with gartrointestinal obstruction, oliguric or anuric renal failure oral rehydration salts should be reconstituted only with water.
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