PROGYNON DEPOT PROGYLUTON GRAVIBINAN GRAVIBINAN CLIMEN CLIMEN PROGYNOVA GLOBINAN GLOBINAN FEMOSTON TRISEQUENS KLIOGEST NOVA JECT OVLOGYN OESTROGEL OESTRODOSE

Dose: 1 to 2 mg
Single Dose: 1.5 (1.5)
Frequency: 24 hourly
Route: PO
Instructions: Normally given in 21 day cycles

Dose:
Single Dose:
Frequency:
Route:
Instructions: Not recommended in this age group

Dose:
Single Dose:
Frequency:
Route:
Instructions: Not recommended in this age group

Estradiol. also known as Oestradiol, Oestradiol. . It is of Natural origin and belongs to Steroid. It belongs to Oestrogen Agonist pharmacological group on the basis of mechanism of action and also classified in Sex Hormones pharmacological group.The Molecular Weight of Estradiol. is 272.40.

Estradiol. is contraindicated in conditions like Hypertension,Vaginal bleeding,Porphyrias,Cardiovascular disease,Oestrogenic sarcoma,Cerebrovascular disease,Haemoglobinopathies,Hyperlipoproteinaemia.

The severe or irreversible adverse effects of Estradiol., which give rise to further complications include Irritability, Gynacomastia, Uterine bleeding, Tachyphylaxis.Estradiol. produces potentially life-threatening effects which include Breast cancer, Endometrial carcinoma. which are responsible for the discontinuation of Estradiol. therapy.The symptomatic adverse reactions produced by Estradiol. are more or less tolerable and if they become severe, they can be treated symptomatically, these include Headache, Depression, Weight gain, Nausea and vomiting, Fluid retention, Breast tenderness.

Estradiol. is primarily indicated in conditions like Menopausal symptoms, Prostatic cancer.

Estradiol. is known to interact with other drugs, the details of drug interactions is as follows:DrugDetailsSeverityOnsetManagementPhenytoin (Na)RifampicinSulphamethizoleConcurrent long-term use of sulfonamides may result in increased incidence of breakthrough bleeding and pregnancy These interactions are sometimes beneficial and sometimes may pose threats to life. Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.

Thyroid Function Test Plasma Cortisol Test Urinary 17-Oxogenic Steroid Test

Drug should not be given to Paediatrics, Pregnant Mothers, patients suffering from Kidney dysfunction, and Neonates.If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.

Tab, Gel Store Below 40°C. Protect from Moisture.

High doses of estrogen used in treatment of malignant disease should be used cautiously in patients with cerebrovascular disorder, coronary artery disease or venous thromboembolism. Estrogens should be used with caution in children, because premature closure of epiphysis may occur resulting in inhibited linear growth and small stature.