SEVENSEAS MVM ONCE A DAY DILCOPLEX DILCOPLEX DILCOPLEX DILCOPLEX REVITALE M REVITALE M REVITALE-B REVITALE-B ENGRAN NUKIK NICTONIC ACID NICOTINIC ACID VITACOMPON HICAP-SS QUANTUM SUPER NICOSUR NICOSUR PREGNA CARE ELKOPLEX EVIVAL ADENOFORT RENAPLEX VIDAYLIN-T DIABETONE NICAPOZ-FOZ NICAPOZ-FOZ DIVASAS FITERNA

Dose: 100 to 200 mg
Single Dose: 150 (150)
Frequency: 8 hourly
Route: PO
Instructions:

Nicotinic Acid also known as Niacin. . It is of Synthetic origin and belongs to Pyridine. It belongs to Lipid lowering agents pharmacological group on the basis of mechanism of action and also classified in Antilipemic Agent pharmacological group.The Molecular Weight of Nicotinic Acid is 123.10. Its pKa is 2.0, 4.8.

Nicotinic Acid is contraindicated in conditions like Diabetes mellitus,Gout,Peptic ulcer.

The severe or irreversible adverse effects of Nicotinic Acid, which give rise to further complications include Urticaria, Jaundice, Jaundice, Hyperuricemia, Cramps, Myalgia, Blurred vision, Acanthosis nigricans, Ichthyosis, Toxic amblyopia, Atrial arrhythmias, Elevated serum aspartate transaminase, Elevated serum creatine kinase.Nicotinic Acid produces potentially life-threatening effects which include Hepatitis, Hepatic failure, Hepatic fibrosis. which are responsible for the discontinuation of Nicotinic Acid therapy.The signs and symptoms that are produced after the acute overdosage of Nicotinic Acid include Flushing, Headache, Pruritus.The symptomatic adverse reactions produced by Nicotinic Acid are more or less tolerable and if they become severe, they can be treated symptomatically, these include Vomiting, Diarrhea, Gastric irritation, Hypotension, Flushing, Faintness, Bloating, faintness, Hypotension.

Nicotinic Acid is primarily indicated in conditions like Hypercholesterolaemia, Hyperlipidemia, Hypertriglyceridaemia, Pellagra, and can also be given in adjunctive therapy as an alternative drug of choice in Acne.

Nicotinic Acid is known to interact with other drugs, the details of drug interactions is as follows:DrugDetailsSeverityOnsetManagementAlcoholAtorvastatinIncreased risk of myopathy when statin (e.g Atorvastatin) given with nicotinic acid (applies to lipid regulating doses of nicotinic acid.Cerivastatin SodiumCerivastatin sodium causes additive toxicity with Nicotinic AcidColestipol (HCl)FluvastatinGlibornurideGliquidoneTechnetium Tc-99m DisofeninChronic, high-dose nicotinic acid therapy may result in poor extraction and elimination of the radiopharmaceutical, mimicking intrinsic hepatocellular disease.Technetium Tc-99m lidofeninNonvisualization of gallbladder may occur due to erthromycin-induced hepatotoxicity. These interactions are sometimes beneficial and sometimes may pose threats to life. Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.

Drug should not be given to Pregnant Mothers, patients suffering from Liver Malfunction, and Neonates.If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.

Tab Store Below 40°C.

Nicotinic acid should be used with caution in patient predisposed to gout because of the elevation of uric acid level. Closely observed patient with gallbladder disease, history of jaundice, liver disease, peptic ulcer, arterial bleeding, glaucoma & diabetic patient for decreased glucose tolerance. Some products contain tartarazine, which causes allergic reaction (including bronchial asthma) in susceptible individuals specially who have aspirin sensitivity. Sholud be given with caution in gouts diabetes mellitus.