Nicotinamide

Nicotinamide is the active form of niacin ( vitamin B 3 ), niacine is a water soluble vitamin, used in multivitamin preparations. It posses antinflammatory properties. it is used topically in the treatment of acne. it is also used to lower blood cholesterol and fat levels.


Brands
VIVIOPTAL SEVENSEAS MVM SEVENSEAS MVM ANGLOVIT ANGLOPLEX EUROVIT IRONMIN ESSENTIALE INJ ESSENTIALE CAP ATCOPLEX -C EUROPLEX ALVIT-B CLOMVIT-F ALVIT F PIZOFEN-V PIZOFEN-V HEPALINA VITARNIN VI-CAPS NEUROTOL MULTIVITAMIN VITA BROOKES PLUS SUPRADYN-N HEPA MERZ VITAMIN B COMPOUND VITAMIN B COMPOUND VITAMIN B COMPOUND SUPRADYN BEROCCA BECOZYM FORTE LITRISON SEPTOPLEX PEMINAL-500 PEMINAL-500 MINAMINO MINAMINO DILCOZYME DILCOZYME DILCOZYME HEPALEX HEPALEX HEPATONE HEPATONE NERVIGOR NERVIGOR SIRON VITACAL XTRA RONUVIT MENDOZA PLEX CAMOVIT-M CAMOPLEX LYSINE CAMOVIT-L CAMOVIT-L CAMOPLEX SUPER CAMOZYME HEPTOCAM HEPTOCAM HEPTOCAM NEW MOLTON-S NEW MOLTON-S BECODON-L LYSOTOP BCOPLEX BCOPLEX BCOPLEX VITAMINOL ETHIBEX -T FORTE ETHIBEX ETHIBEX LIVOTONE CYNODOX-C LYSINE CYNODOX-SF CYNODOX-C FORTE EPLAZYME EPLAZYME EPLAZYME ORACAP-T MULTIVITAMIN GEOVIT FORTE VITAG UNIPLEX THERAGRAN-H FESOVIT-Z FESOVIT-Z CYTEXIN WELLCOSINE FEFOL VIT SPANSULE FEMOCAL PLUS CYANOPLEX SOLUTION 1 MULTICAP-M VITRONEX UNIHAEM UNIHAEM VITANOL VITANOL VITANOL PHOZFODEX MULTINA PLUS MULTINA PLUS MULTINA PLUS MULTINA MAX MULTINA MAX MULTINA MAX CAL-V-CON SUMMERVITA SUMMERVITA MULTINA-33 MULTINA-33 MULTINA-33 ORNAMIN ZYMOPLEX ZYMOPLEX PREGNOVIT REGNUM KAYCIPLEX-L KAYCIPLEX ENERVIN KARMAPLEX HEMOTON-S HEMOTON-S HEMOVIT PEXOVIT PEXOVIT PEXOVIT HICAP-M ENERVIT HEPATOVIT NEUROSTRESS-C NEUROSTRESS NEUROSTRESS NEUROSTRESS NEUROSTRESS-L PREGNATAL SOVIT-M LEAMAX-C MARVIPLEX MARVIPLEX VITAVIT VITAVIT VITAVIT THERIN VIT THERIN-M SUPER QUANTUM GOLD THERAPLEX COMBIPLEX FORTE CURACAP-T COMBIPLEX LYSOPLEX LYSOPLEX LYSOPLEX VITCOM BINIPLEX BINIPLEX RUBEX HONEYPLEX MAZIVIT M VEENA FORTE VEENA FORTE UNIVIT-M ENZOVIT MEDIPHAKOL MIOBI NEUROBEC ZYGEST MULTICAL-PLUS BIOLYSINE SANTEVINI PLUS MOSEGOR-V MOSEGOR-V OROPLEX OROPLEX OPALEX EXTRA OPALEX EXTRA OPALEX -L OPALEX MULTI OPALEX MULTI POLYZYMA SPARTATE HANYBEC MULTINAF POLYBION Z POLYBION STRONG POLYBION FORTE C POLYBION FORTE C MULTIBIONTA-M MULTIBIONTA-M POLYBION FORTE POLYBION FORTE MULTIBIONTA MULTIBIONTA MULTIBIONTA SANGOBION VITERRA THERAPEUTIC VITALET-M VITAMIN B COMPOUND FERRODIN-F FERRODIN POLYVIT-M UNICAP-M VI-MAGNA UNICAP UNICAP-T LYSOVIT STRESSTABS CENTRUM MATERNA ABDEC ABDEC LEDERPLEX VITALET-H OSSO PLUS AMINOVEL-600 VIKONON FORTE REVITON REVITON ARUNAPLEX ARUNAPLEX BECE VIT BECE VIT CESTONIL PLUS CESTONIL PLUS ORAVIT-H JETEPAR JETEPAR JETEPAR JETEPAR ALDALYSINE ALDALYSINE CALMIN-600 LEVIJON SEMOGLOBIN VIOPHOS-B GLYVISOL ENRICH GENATOSAN GENATOSAN PLUS IRON DIGEPLEX VITAGLOBIN UNESKO-T UNESKO-T VASEDEX-C MULTONIC FERVIT FERVIT VASEDEX-L CALIX DIADYNAM-G DYNAMIN-V WILGRAN-M HEMOTIN MVEM-21 HEPA-ZAF GROVIT GROVIT GROVIT-B BC-LYSE VITALEX TOXINIL WILPLEX AQUA VIT APPEVIT CALCEE PLUS NUTRITION-12 HIGH-C PLUS EFER-VIT ENERGIN TAZIN TAZIN NUTRICAP-M MYFER MYFER THERON-F THERON-F THERON-F AMROTON AMROTON AKSOHEP HAEM BLOMIC AMVIT AMVIT ZYVIT DELMIN DELCOBEX MYTON-S MYTON-S MYTON-S ENGOR ENGLISH-PLEX-L ORNIVIT ENERGY PLUS MB-VITA MULTIMIN MULTIMIN LISKOPLEX LISKOPLEX LISKOPLEX VITAZYME FFERROPRO GERICAP EFFECO TONIC POLY CAL PLUS MEGAZYME PLEXOVIT-L PLEXOVIT PLEXOVIT PLEXOVIT VITONE SCHAZOOS B-TONIC ACE-BEX ADENOFORT ARDIPLEX EROGLOBIN EROGLOBIN K-CEE PLUS NEUROVIT-M UNIBEX-T DAVIPLEX CALCEPLEX FORTE AMINOVIT MULTITONE Y-GOGIN MULTITINE B.COMPLEX B.COMPLEX B.COMPLEX B.COMPOUND B.COMPLEX FORTE NEUROPLEX GENIPLEX BECOSCOT SANZYM HEMOCAL CAPROVIT DEXIPLEX-F VISIONACE MULTEX REMOPLEX REMOPLEX REMOPLEX REMOPLEX VIDAYLIN-M VIDAYLIN-M SURBEX-Z SURBEX-Z SURBEX SURBEX VIDAYLIN-L VI-DAYLIN VI-DAYLIN VI-DAYLIN PRAMET-FA PRAMET-FA OPTILETS-M IBERET 500 GRADUMET IBERET 500 GRADUMET DAYALETS IBERET-500 IBERET-500 IBERET FOLIC-500 GRADUMET IBERET FOLIC-500 GRADUMET BECEFOL BECEFOL BECEFOL BEJECTAL-T BEJECTAL-T BEJECTAL BEJECTAL IBEROL-F PERFECTIL ACTI-TONE OLIVIT OLIVIT OLIVIT ENEMIK ENEMIK M. BROPLEX M. BROPLEX M. BROPLEX M. BROPLEX M-BROVIT M-BROVIT VITATHERA VITATHERA-C REVERZ AMINOSOL S.V VITIRON C ZOVIT POLYVIT FERATONIC-VIT GERIATRIC PHARMATON GERIATRIC PHARMATON ORNITATE ORNITATE MERZEPA MERZEPA
Adult Dose
Dose: 1.428 to 3.571 mg/kg
Single Dose: 2.5 (2.4995)
Frequency: 24 hourly
Route: IV
Instructions: -
Neonatal
Dose: 0.625 to 1.25 mg/kg
Single Dose: 0.94 (0.9375)
Frequency: 24 hourly
Route: Oral
Instructions:
Paedriatic
Dose: 1 mg/kg
Single Dose: 1 (1)
Frequency: 24 hourly
Route: Oral
Instructions: -
Characteristics
Nicotinamide also known as Niacinamide. Nicotinamide areorbate is the derivative of Nicotinamide. It is of Natural origin and belongs to Amide. It belongs to Vitamin, Water Soluble pharmacological group.The Molecular Weight of Nicotinamide is 122.10. It is weakly alkaline drug, 4.49% solution of the drug is isotonic.
Contraindications
'Nicotinamide is contraindicated in conditions like Wilson''s disease,Hypersensitivity to any component of product.'
Effects
Nicotinamide produces potentially life-threatening effects which include Hepatotoxicity, Cholestasis, Portal fibrosis. which are responsible for the discontinuation of Nicotinamide therapy.The signs and symptoms that are produced after the acute overdosage of Nicotinamide include Transient liver dysfunctioning.The symptomatic adverse reactions produced by Nicotinamide are more or less tolerable and if they become severe, they can be treated symptomatically, these include Headache, Fatigue, Nausea, Palpitation, Tachycardia, Sweating, Chills, Flushing, Heart burn, Faintness, Sore throat, Dry hair, Tautness of the Face, Inability of eye focusing, Oedema, faintness, Dypnoea, Tachycardia, Sensation of Heat.
Indications
Nicotinamide is primarily indicated in conditions like Hartnup disease, Inflammatory skin disease, Vitamin deficiency.
Interactions
Nicotinamide is known to interact with other drugs, the details of drug interactions is as follows:DrugDetailsSeverityOnsetManagementCarbamazepineCerivastatin SodiumCerivastatin sodium causes additive toxicity with NicotinamidePrimidonePrimidone These interactions are sometimes beneficial and sometimes may pose threats to life. Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.
Interfrence
Risks
Drug should not be given to Paediatrics, Geriatrics, and Neonates.If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.
Storage
Tab Store in a well closed container, Below 40°C.
Warnings
Nicotinamide should be used with caution in patients with history of heart disease, high blood pressure or insulin-dependent diabetes. This is not recommended for use during pregnancy or lactation.
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