Amoxicillin is oral semisynthetic aminopenicillin similar to ampicillin. Amoxicillin is more stable to gastric acids and more bioavailable than other penicillins. It inhibits the 3rd and final stage of bacterial cell wall synthesis by binding to specific penicillin-binding proteins PBPs that are located inside the bacterial cell wall and are responsible for several steps in the synthesis of the cell wall. Chemically Amoxicillin is D-(-)-a-amino-p-hydroxy-benzyl penicillin. Amoxicillin is a broad spectrum antibiotic and has bactericidal activity against many gram positive and gram negative bacteria. Antibiotics require constant drug level in body for therapeutic effect. This is achieved by taking the drug at regular intervals of time throughout the day and night as prescribed. Amoxicillin is important to take the drug for the full time period as prescribed. If you discontinue the drug it may result in ineffective treatment.
Indications
Amoxicillin is primarily indicated in conditions like Abscesses, Acute bronchitis, Bacteriuria, Bronchitis, Carbuncles, Cellulitis, Chronic bronchitis, Cystitis, Dental abscess, Dental abscess (short-course), Endocarditis, Furunculosis, Gonorrhoea, Gynecological infections, Haemophilus influenzae infections, Helicobacter pylori eradication, Infected wounds, Inflammatory bowel disease, Lower respiratory tract infections, Meningitis, Metastatic, Metastatic colorectal cancer, Mild to moderate chronic heart failure, Muscle relaxation (short duration) for surgery, Muscle relaxation during intensive care, Muscle relaxation for surgery or intubation, Osteomyelitis, Otitis media, Parathyroid fever, Peritonitis, Pharyngitis, Pneumonia, Puerperal sepsis, Pyelonephritis, Septic abortion, Septicaemia, Sinusitis, Skin infections, Soft tissue infections, Surgical infections, Syphilis, Systemic infections, Tonsillitis, Typhoid, Urinary tract infection.