Amodiaquine

Amodiaquine is a 4-aminoquinoline antimalarial with an action and uses similar to that of chloroquine. Amodiaquine is not recommended for the prophylaxis of malaria. Amodiaquine is used to treat malaria (intermittent or remittent disease characterized by attacks of chills, fever, and sweating and caused by a parasitic protozoan transferred to the human bloodstream by an anopheles mosquito).

Brands
DOSAQUIN ARAQAL ARAQAL ARAQAL ARAQAL ARAQAL ARAQAL ARAQAL ARAQAL ARAQAL NOVOQUINE NOVOQUINE NOVOQUINE MUNOQUINE MUNOQUINE BASOQUIN BASOQUIN AMOQUINE AMOQUINE SEMOQUINE SEMOQUINE UNESOQUINE UNESOQUINE SPAQUINE AMDAQUIN AMDAQUIN AMDAQUIN PROZOQUIN PROZOQUIN CONQUIN
Adult Dose
Dose: 35 mg/kg
Single Dose: 35 (35)
Frequency: As recommended.
Route: PO
Instructions: For 3 days.
Neonatal
Dose: 6.25 mg/kg
Single Dose: 6.2 (6.25)
Frequency: As recommended.
Route: oral
Instructions: Once a week
Paedriatic
Dose: 5 to 10 mg/kg
Single Dose: 7.5 (7.5)
Frequency: As recommended.
Route: Oral
Instructions: Once a Week
Characteristics
Amodiaquine HCl is the derivative of Amodiaquine. It is of Synthetic origin and belongs to Quinoline Phenol. It belongs to Antiplasmodial pharmacological group on the basis of mechanism of action and also classified in Antimalarial Agent pharmacological group.The Molecular Weight of Amodiaquine is 464.80.
Contraindications
Amodiaquine is contraindicated in conditions like Malaria prophylaxis.
Effects
The severe or irreversible adverse effects of Amodiaquine, which give rise to further complications include Liver damage.Amodiaquine produces potentially life-threatening effects which include Blood dyscrasias, Lupus erythematosus. which are responsible for the discontinuation of Amodiaquine therapy.The symptomatic adverse reactions produced by Amodiaquine are more or less tolerable and if they become severe, they can be treated symptomatically, these include Weakness, Nausea, Vomiting, Diarrhea, Abdominal cramps, Tinnitus, Irregular heart beat, Termors, General malaise, Skin pigmentation, Palate pigmentation, Nail-beds pigmentation.
Indications
Amodiaquine is primarily indicated in conditions like Malaria, Nephrogenic and partial pituitary diabetes insipidus.
Interactions
No data regarding the interactions of Amodiaquine was found.
Interfrence
Risks
Drug should not be given to Pregnant Mothers.If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.
Storage
Tab Store in a well closed container.
Warnings
It should be used with caution in patients allergic to peanuts, not to be used on broken, infectious skin. It should be used with caution in blockage of the gut (intestinal obstruction).
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