Naftidrofuryl (Oxalate)

Naftidrofuryl (Oxalate) is used as a vasodilator in the treatment of peripheral and cerebral vascular disorders. Naftidrofuryl (Oxalate) is also claimed to enhance cellular oxidative capacity thereby protecting cells against the results of ischaemia.


Brands
Adult Dose
Dose: 8.571 mg/kg
Single Dose: 8.6 (8.571)
Frequency: As recommended.
Route: PO
Instructions: For at least 3 months
Neonatal
Dose: Not indicated in this age group
Single Dose:
Frequency:
Route:
Instructions:
Paedriatic
Characteristics
Naftidrofuryl (Oxalate) also known as Nafroyl, Nafroyl. . It is of Synthetic origin and belongs to Furfuryl Propionate. It belongs to Vasodilators pharmacological group on the basis of mechanism of action and also classified in Antihypertensive Agents pharmacological group.The Molecular Weight of Naftidrofuryl (Oxalate) is 473.60. Its pKa is 8.7.
Contraindications
Naftidrofuryl (Oxalate)
Effects
The severe or irreversible adverse effects of Naftidrofuryl (Oxalate), which give rise to further complications include Hepatitis, Hepatic failure.The signs and symptoms that are produced after the acute overdosage of Naftidrofuryl (Oxalate) include Hypotension, Convulsions, Unconsciousness.The symptomatic adverse reactions produced by Naftidrofuryl (Oxalate) are more or less tolerable and if they become severe, they can be treated symptomatically, these include Nausea, Rashes, Epigastric pain.
Indications
'Naftidrofuryl (Oxalate) is primarily indicated in conditions like Peripheral vascular disease, Raynaud''s phenomenon, Sedative in combined anaesthesia, and can also be given in adjunctive therapy as an alternative drug of choice in Alzheimer''s disease, Dementia.'
Interactions
No data regarding the interactions of Naftidrofuryl (Oxalate) was found.
Interfrence
Risks
Drug should not be given to Paediatrics, and Neonates.If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.
Storage
Caps Store Below 20°C. Protect from Sunlight.
Warnings
A sufficient amount of liquid should be taken during treatment to maintain an adequate level of diuresis.
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