VESPIN AMDOCAL PRESCARD BESCARD BESCARD ORELOP ORELOP CARDIOSIL CARDIOSIL AMODIP AMODIP AMODIP PRESACORD CORINOR CORINOR NORVASC NORVASC AMLOCARD AMLOCARD AMLOCARD CORDIUM CABOK CABOK RAVAPINE RAVAPINE RAVAPINE RAVAPINE CA-B CA-B AMLOPIN SOFVASC SOFVASC SOFVASC SOFVASC SOFVASC SOFVASC SOFVASC SOFVASC SOFVASC ZODIP HYPOTIN HYPOTIN NEOPRES NEOPRES LODOPIN LODOPIN LODOPIN CALOC CALOC ANAM ANAM RYDEM RYDEM RYDEM SWINT SWINT HARTVASC-PLUS HARTVASC-PLUS HARTVASC-PLUS ONATO ONATO LODIPIN LODIPIN AMRX AMRX AMOLIN AMPRESS AMPRESS AMDIPINE AMDIPINE AMDIPINE AMDIPINE QUVASC QUVASC QUVASC CORAM CORAM LODIVASC AMLOBEST AMLOBEST SICKNOR SICKNOR AMLOWAN HIBLOHIT CARDIOVASC CARDIOVASC CARDIOVASC ZAMLO CORDFED ENDIP ENDIP MIOSIL MIOSIL SALOME ZAMLO-H MODOPINE MODOPINE REVLOC REVLOC REVLOC PLUS AMLOD AML AMLOTAC AMLOTAC HIBIOHIT HYPERCOR HYPERCOR MEGADIP MEGADIP ENALATAC ENALATAC WINCORAM WINCORAM RASDIPIN ADOPTIN CANTA CANTA CANTA-D VASODIPINE AMLOPAL AMLOPAL ADOPTINE AMLODIP AMLODIP AMOTEL AMOTEL DIPCARE AVIANT AVIANT CORCONT CORCONT ENVAS ENVAS AMLOMAK AMLOMAK FARLOD FARLOD VASODIL HYPOCARD MEVODIP AMLAT AMLAT AMLAT EXFORGE HCT EXFORGE HCT EXFORGE HCT EXFORGE HCT EXFORGE HCT HODIP HODIP HYPRES HYPRES LEAF AMOVASC ATEASE ATEASE ATEASE ATEASE COMBITROL COMBITROL CARDIOCARE CARDIOCARE AMLOSYL CADWIN CADWIN AM DESCOL AM DESCOL AM DESCOL AM DESCOL AM DESCOL AM DESCOL AM DESCOL AM DESCOL CADUET CADUET VATLO AMLOTIN AMLOTIN AMLOTIN AMTORIN AMTORIN AMTORIN PLUS CARDIOVASC DUO CARDIOVASC DUO SOFVASC-V CARA-PIN CARA-PIN AMLOZAN AMLOZAN AMLOZAN AMLOZAN LOPIN LOPIN VAMLODIP AMSTAN AMSTAN AMSTAN AMSTATIN AMSTATIN AMTAS AMTAS AMTAS AMTAS AMTAS AM-TELSAN AM-TELSAN AM-TELSAN AM-TELSAN ARDEPIN ARDEPIN AVCARD AVCARD AVCARD AVSAR AVSAR AVSAR CO-ATORAP CO-ATORAP CO-ATORAP CO-ATORAP COMCARB COMCARB COMCARB COMCARB HYPERSTATIN LODIS LODIS LODIS RATOR PLUS RATOR PLUS RATOR PLUS RATOR PLUS RATOR PLUS TAVIST PLUS TAVIST PLUS TAVIST PLUS TAVIST PLUS TAVIST PLUS TAVIST PLUS TELMIS-A TELMIS-A TELMIS-A TELMIS-A TELMIS-A VALSAN-AM VALSAN-AM AMLOPRO AMLOPRO AMLOSAF AMLOSAF AMOSTIN AMOSTIN AMVAZAM CO-CARDIOVASC CO-CARDIOVASC CORSAFE CORSAFE DIPIVAS DIPIVAS LIPICA PLUS LIPICA PLUS LIPICA PLUS LIPICA PLUS LIPICA PLUS LIPICA PLUS LIPICA PLUS MIDOPINE MIDOPINE NENCURE NENCURE NEWDAY NEWDAY NEWDAY NEWDAY NEWDAY NUVASC NUVASC ORION CA ORION CA ORION CA ORION CA SOFVASC PLUS VASTAPINE VASTAPINE AMOSTATIN AMOSTATIN CORSAFE-AT CORSAFE-AT COVERSAM COVERSAM COVERSAM COVERSAM DIOPLUS DIOPLUS DIOPLUS EXTOR EXTOR EXTOR G-SAC MLOW MLOW OMSANA AM OMSANA AM OMSANA AM TAROVASC TAROVASC VASIC VASIC VASSODIP VASSODIP VASTOR-AM VASTOR-AM AMPER AMPER BENICAR PLUS BENICAR PLUS CO-EXTOR CO-EXTOR CO-EXTOR CONEXT LIPINOX LISONORM MISAR-AM MISAR-AM TELEPINE TELEPINE TELEPINE TELEPINE TELEPINE TELEPINE TELEPINE TRI-VALSAN TRI-VALSAN TRI-VALSAN TRI-VALSAN TRI-VALSAN TRI-VALSAN VALAM VALAM VALAM-H VALAM-H VALAM-H VALAM-H VALAM-H PERINDOPINE PERINDOPINE AMVASC AMVASC AMLOMED AMLOMED CAPRINZA CAPRISK AMODIP PLUS AVOTIN VALTEC AM VALTEC AM VALTEC AM EXFORGE EXFORGE EXFORGE AMLOFINE AMLOFINE ANGIPIN ANGIPIN BESIPINE LOW VASE LOW VASE OLMEDIP OLMEDIP OLMEDIP OLMEDIP PROVASC S-DIP S-DIP SOFVASC-OLM SOFVASC-OLM SOFVASC-OLM AMODIP-V AMODIP-V AMODIP-V VALKEN-A VALSAR-M VALSAR-M VALSAR-M AVASCAR PLUS AVASCAR PLUS

Dose: 5 to 10 mg
Single Dose: 7.5 (7.5)
Frequency: 24 hourly
Route: PO
Instructions: Use 2.5 mg/dose QD PO, in small & fragile geriatric patients or those with hepatic insufficiency.Maximum dose: 10 mg/24hr

Amlodipine is the derivative of Amlodipine (Besylate). It is of Synthetic origin. It belongs to Calcium L-channel antagonist pharmacological group on the basis of mechanism of action.

Amlodipine (Besylate) is contraindicated in conditions like Sinoatrial node disease,Hypersensitivity,Aortic stenosis.

The severe or irreversible adverse effects of Amlodipine (Besylate), which give rise to further complications include Peripheral edema, Sinus bradycardia.Amlodipine (Besylate) produces potentially life-threatening effects which include Myocardial infarction. which are responsible for the discontinuation of Amlodipine (Besylate) therapy.The signs and symptoms that are produced after the acute overdosage of Amlodipine (Besylate) include Hypotension, Bradyarrhythmias, Congestive heart failure, Conduction system Delay.The symptomatic adverse reactions produced by Amlodipine (Besylate) are more or less tolerable and if they become severe, they can be treated symptomatically, these include Flatulence, Dizziness, Vertigo, Headache, Drowsiness, Fatigue, Nausea, Vomiting, Diarrhea, Palpitation, Tremors, Constipation, Abdominal pain, Blurred vision, Peripheral edema, Skin erythema, Facial flushing, Hypotension, Coughing, Flushing, Syncope, Wheezing, dysthesia.

Amlodipine (Besylate) is primarily indicated in conditions like Angina pectoris, Essential hypertension, Hypertension, Prophylaxis of angina, Vasospastic angina.

Amlodipine (Besylate) is known to interact with other drugs, the details of drug interactions is as follows:DrugDetailsSeverityOnsetManagementAlcoholEnhanced hypotensive effect when calcium-channel blockers (e.g Amlodipine) given with Alcohol.AtenololEnhanced hypotensive effects when calcium-channel blockers (e.g Amlodipine) given with beta-blockers (e.g Atenolol)CalcitoninCarbamazepineCarbamazepine may increase the metabolism, via CYP isoenzymes, of Amlodipine.ModerateMonitor for reduced therapeutic effects of Amlodipine if Carbamazepine is initiated or the dose is increased. Cimetidine (HCl)Cimetidine may decrease the metabolism of Amlodipine. ModerateMonitor for increased effects of Amlodipine if Cimetidine is initiated/dose increased, and decreased effects if Cimetidine is discontinued/dose decreased. DiazoxideEnhanced hypotensive effect when Diazoxide given with Amlodipine.DigoxinAmlodipine increases plasma concentration of digoxinErythromycinErythromycin may decrease the metabolism, via CYP isoenzymes, of Amlodipine. ModerateMonitor for increased therapeutic effects of Amlodipine if Erythromycin is initiated/dose increased, or decreased effects if Erythromycin is discontinued/dose decreased. Nitroglycerinsimultaneous use of nitroglycerin and ca channel blockers may cause orthostatic hypotension Phenytoin (Na)Amlodipine may decrease the metabolism of Phenytoin. ModerateMonitor for Phenytoin toxicity when Amlodipine is initiated/dose increased, or decreased Phenytoin effects if Amlodipine is discontinued/dose decreased. QuinidineAmlodipine may decrease the serum concentration of Quinidine. ModerateMonitor for decreased Quinidine effects if Amlodipine is initiated/dose increased or increased effects/toxicity if Amlodipine is discontinued/dose decreased. RitonavirIncreased plasma concentration of Amlodipine when given with antivirals (e.g Ritonavir).TadalafilSmall reductions in blood pressure may occur following coadministration of tadalafil and Amlodipine (Besylate).TheophyllineAmlodipine increases plasma concentration of theophylline.VORICONAZOLEoriconazole may increase the serum concentration of amiodarone by decreasing its metabolism. discontinued or dose changedWarfarin (Na) These interactions are sometimes beneficial and sometimes may pose threats to life. Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.

Drug should not be given to Paediatrics, Pregnant Mothers, and Neonates.If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.

Tab Store in a well closed container, Below 40°C. Protect from Sunlight and Moisture.

Amlodipine should be used with caution in patients with heart, liver disease or if have any allergy. Limit intake of alcohol while taking this drug. This medication should be used with extreme caution during pregnancy.