Dose: 0.714 to 1.904 mg/kg
Single Dose: 1.3 (1.309)
Frequency: 8 hourly
Route: PO
Instructions: -

Dose:
Single Dose:
Frequency:
Route:
Instructions: Not recommended in this age group

Dose:
Single Dose:
Frequency:
Route:
Instructions: Not recommended in this age group

. It is of Synthetic origin and belongs to Piperidine. It belongs to Hypnotic pharmacological group on the basis of mechanism of action. The Molecular Weight of Methyprylone is 183.20. Its pKa is 12.0.

Methyprylone is contraindicated in conditions like Alcohol dependence,Depression,Porphyria,Sleep apnea syndrome.

The severe or irreversible adverse effects of Methyprylone, which give rise to further complications include Hallucinations, Anxiety, Polyuria, Seizures, Dependence, Hyperreflexia.Methyprylone produces potentially life-threatening effects which include Pulmonary edema, Coma, Respiratory depression, Hypotension. which are responsible for the discontinuation of Methyprylone therapy.The signs and symptoms that are produced after the acute overdosage of Methyprylone include Coma, Hyperthermia, Respiratory depression, Pupillary changes, Hypothermia, Nystagmus, Dysarthria.The symptomatic adverse reactions produced by Methyprylone are more or less tolerable and if they become severe, they can be treated symptomatically, these include GI disturbance, CNS disturbances.

Methyprylone is primarily indicated in conditions like Insomnia.

No data regarding the interactions of Methyprylone was found.

Holotorff Koch Modification of the Zimmerman Test for determinatin of 17-Ketosteroids

Drug should not be given to Pregnant Mothers, patients suffering from Kidney dysfunction, patients suffering from Liver Malfunction, and Neonates.If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.

Store at room temperature, .

Patient should observe caution while driving or performing other task requiring alertness because it may produce dizziness. Total daily intake should not exceed to 400 mg. Methyprylone should be used with caution in patients with kidney and liver disease. Perform periodic blood counts if use over prolonged period. Patients should be warned against the concomitant use of methyprylone and alcohol or other CNS depressants. Habituation and physical dependence have been reported to occur when excessive doses are taken over an extended period of time.