Methylcellulose

Indigestible plant residue used as a lubricating agent in the pharmaceutical preparations and as a purgative. it adsorbs water increases faecal bulk and promotes bowel movement. Methylcellulose is in used in the treatment of diarrhea or constipation and in the treatment of irritable bowel syndrome and spastic colon.

Brands
VECHLOR
Adult Dose
Dose: 7.142 to 14.28 mg/kg
Single Dose: 11 (10.711)
Frequency: 24 hourly
Route: PO
Instructions: -
Neonatal
Dose: 50 mg/kg
Single Dose: 50 (50)
Frequency: 12 hourly
Route: Oral
Instructions:
Paedriatic
Dose: 1 g
Single Dose: 1 (1)
Frequency: 12 hourly
Route: Oral
Instructions: 7-12 years
Characteristics
. It is of Semi Synthetic origin and belongs to CHO. It belongs to Laxatives pharmacological group on the basis of mechanism of action.
Contraindications
Methylcellulose is contraindicated in conditions like Intestinal obstruction,Dehydration.
Effects
The symptomatic adverse reactions produced by Methylcellulose are more or less tolerable and if they become severe, they can be treated symptomatically, these include Nausea, Diarrhea, Fluid retention, Bloating distension.
Indications
Methylcellulose is primarily indicated in conditions like Constipation, Diarrhoea, Diverticulitis, Irritable bowel syndrome, and can also be given in adjunctive therapy as an alternative drug of choice in Obesity.
Interactions
Methylcellulose is known to interact with other drugs, the details of drug interactions is as follows:DrugDetailsSeverityOnsetManagementNeostigmine These interactions are sometimes beneficial and sometimes may pose threats to life. Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.
Interfrence
Risks
Drug should not be given to Neonates.If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.
Storage
Tab, Caps, Eye Drops, Powder Store Below 40°C. Protect from Sunlight, Moisture and Heat.
Warnings
Methylcellulose should be used only if clearly needed during pregnancy. It should be used with caution in patients with any illness or allergy. It should not be used in Infective bowel disease, Oesophageal obstruction, faecal Impaction.
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