Dose: 50 to 120 mg
Single Dose: 85 (85)
Frequency: As recommended.
Route: IV
Instructions: Initial dose; It provieds about 5-7 minutes of anesthesia.

belongs to Barbiturate. It belongs to Chloride Channel opener (Gaba operated) pharmacological group on the basis of mechanism of action and also classified in General Anesthetics pharmacological group.The Molecular Weight of Methohexitone (Na) is 284.30. Its pKa is 8.3.

Methohexitone (Na) is contraindicated in conditions like Epilepsy,Porphyria.

The severe or irreversible adverse effects of Methohexitone (Na), which give rise to further complications include Gangrene, Thrombosis.Methohexitone (Na) produces potentially life-threatening effects which include Bronchospasm, Cardiovascular collapse. which are responsible for the discontinuation of Methohexitone (Na) therapy.The symptomatic adverse reactions produced by Methohexitone (Na) are more or less tolerable and if they become severe, they can be treated symptomatically, these include Local pain.

Methohexitone (Na) is primarily indicated in conditions like Induction of anaesthesia.

Methohexitone (Na) is known to interact with other drugs, the details of drug interactions is as follows:DrugDetailsSeverityOnsetManagementAspirinCyclizineHydrocortisoneHydromorphoneProbenecidPromethazine (HCl)SulfanilamideVecuronium (Br) These interactions are sometimes beneficial and sometimes may pose threats to life. Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.

Drug should not be given to Pregnant Mothers, Cardiac / Hypertensive Patients, Geriatrics, and Neonates.If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.

Inj

Exercise caution in patients with impaired function of respiratory, circulatory, kidney, liver or endocrine system. Avoid extravascular and intra-arterial injection of methohexitone because it may cause pain, swelling, ulceration, necrosis and gangrene of extremities respectively.