PENTASA MESAZINE COLTAB COLTAB MASACOL MASACOL ASACOL ASACOL COLZINE

Dose: 800 mg
Single Dose: 800 (800)
Frequency: 8 hourly
Route: PO
Instructions:

Dose:
Single Dose:
Frequency:
Route:
Instructions: Not recommended in this age group

Dose: 10 mg/kg
Single Dose: 10 (10)
Frequency: 8 hourly
Route: Maintanance ,To maximum of 500mg
Instructions:

Mesalazine also known as 5- Amino Salicylic Acid. . It is of Synthetic origin and belongs to Aminosalicylic Acid. It belongs to Ulcerative Colitis remedies (GI) pharmacological group on the basis of mechanism of action and also classified in Analgesics and Anti-inflammatory Agents and Antipeptic Ulcerant pharmacological group.The Molecular Weight of Mesalazine is 153.10. Its pKa is 2, 5.8, 12.

Mesalazine is contraindicated in conditions like Hypersensitivity.

The severe or irreversible adverse effects of Mesalazine, which give rise to further complications include Hepatitis, Bronchospasm, Bronchospasm, Nephrotic syndrome, Blood dyscrasias, blood dyscrasias.Mesalazine produces potentially life-threatening effects which include Myocarditis, Pericarditis. which are responsible for the discontinuation of Mesalazine therapy.The symptomatic adverse reactions produced by Mesalazine are more or less tolerable and if they become severe, they can be treated symptomatically, these include Headache, Nausea, Vomiting, Alopecia, Diarrhea, Fever, Rashes, Hair loss, Chest pain, Leukopenia, Paresthesias, Abdominal discomfort, Alopecia.

'Mesalazine is primarily indicated in conditions like Crohn''s disease, Ulcerative colitis.'

No data regarding the interactions of Mesalazine was found.

Assay methods for Glucose, Bilirubin, Urobilinogen, Phenylketones, VMA and Urinary Proteins

Drug should not be given to Paediatrics, Pregnant Mothers, patients suffering from Kidney dysfunction, patients suffering from Liver Malfunction, and Neonates.If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.

Tab, Supposotories, Enema Store in a well closed container, . Protect from Sunlight.

Avoid mesalazine in patients with impaired renal function or salicylate or sulfite hypersensitivity. It should be used with caution in elderly. Avoid use in children under 2 years of age. If blood dyscrasia is suspected treatment should be stopped immediately and blood count should performed.