MEPROGESIC POLYZYMA-T PANOGESIC

Dose: 400 mg
Single Dose: 400 (400)
Frequency: 8 hourly
Route: PO
Instructions: Frequency may be increased upto 4 times/day if needed.

Dose:
Single Dose:
Frequency:
Route:
Instructions: Not recommended in this age group

Dose:
Single Dose:
Frequency:
Route:
Instructions: Not recommended in this age group

. It is of Natural origin and belongs to Carbamate. It belongs to Psychotropic Drugs pharmacological group on the basis of mechanism of action and also classified in Antianxiety Agent pharmacological group.The Molecular Weight of Meprobamate is 218.30. Its pKa is 14.

Meprobamate is contraindicated in conditions like Alcohol dependence,Porphyrias,Respiratory depression,Acute pulmonary insufficiency,Breast feeding.

The severe or irreversible adverse effects of Meprobamate, which give rise to further complications include Convulsions, Nausea, Vomiting, Tachycardia, Fever, Thrombocytopenia, Hypotension, Angioneurotic edema, Bronchospasm, Hypotension, Bronchospasm, Agranulocytosis, Thrombocytopenic purpura, Chills, parasthesia, Tachycardia.Meprobamate produces potentially life-threatening effects which include Porpyhria. which are responsible for the discontinuation of Meprobamate therapy.The signs and symptoms that are produced after the acute overdosage of Meprobamate include Coma, Shock, Vasomotor collapse, Respiratory collapse.The symptomatic adverse reactions produced by Meprobamate are more or less tolerable and if they become severe, they can be treated symptomatically, these include Dizziness, Drowsiness, Ataxia, Nausea, Diarrhea, Skin rashes, Sedation, Skin rashes, dizziness, Ataxia.

Meprobamate is primarily indicated in conditions like Anxiety, Insomnia, Musculoskeletal disorders.

Meprobamate is known to interact with other drugs, the details of drug interactions is as follows:DrugDetailsSeverityOnsetManagementAlcoholEthinyloestradiolGriseofulvinPhenytoin (Na)RifampicinWarfarin (Na) These interactions are sometimes beneficial and sometimes may pose threats to life. Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.

Test for Oestriol by Brown-Kober Procedure Test for 17-OH Corticosteroids by Glenn-Nelson Method and Porter Silber Reaction Test for Barbiturates by Frings TLC Procedure Test for 17-Ketogenic and 17-Ketosteroids by Zimmerman Reaction

Drug should not be given to Paediatrics, Pregnant Mothers, and Neonates.If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.

Tab

Meprobamate should be used with caution in patients with respiratory disease; muscle weakness; epilepsy,depression (may include seizures); history of drug or alcohol abuse; marked personality disorder; pregnancy; elderly and debilitated; hepatic and renal impairment; avoid prolonged use abrupt withdrawl may precipitate convulsions. DRIVING: Drowsiness may affect performance of skilled tasks (e.g driving); effects of alcohol enhanced.