Menotrophin

Menotrophin contains follicle stimulating hormone (FSH) and lutenizing hormone (LH) glycoproteins of pituitary origin in a 1:1 ratio. it is prepared from the urine of the postmenopausal women. it is administered intramuscularly. It is used to stimulate ovulation.


Adult Dose
Dose: 75 to 300 IU
Single Dose: 190 (187.5)
Frequency: 24 hourly
Route: IM
Instructions: Followed by 5000-10,000U 1 day after the last dose.
Neonatal
Dose: Not use in children
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Frequency:
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Paedriatic
Dose: Not indicated in this age group
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Characteristics
. It is of Natural origin and belongs to Steroid. It belongs to Sex Hormones and Gonadotropin, Ovulation Stimulator pharmacological group.The Molecular Weight of Menotrophin is 36.00.
Contraindications
Menotrophin is contraindicated in conditions like Testicular tumors,Ovarian dysgenesis,Premature menopause,Tubal disease,Testicular failure,Pituitary tumor.
Effects
The severe or irreversible adverse effects of Menotrophin, which give rise to further complications include Pulmonary edema, Gynacomastia, Thromboembolism.Menotrophin produces potentially life-threatening effects which include Ovarian hyperstimulation syndrome (OHSS). which are responsible for the discontinuation of Menotrophin therapy.The symptomatic adverse reactions produced by Menotrophin are more or less tolerable and if they become severe, they can be treated symptomatically, these include Tiredness, Headache, Fever, Abdominal pain, Weight gain, Fluid retention, Mood swings, Joint pain.
Indications
Menotrophin is primarily indicated in conditions like Cryptorchidism (undescended testes), Follicular growth stimulation, Hypogonadotrophic hypogonadism, Male infertility, Superovulation.
Interactions
No data regarding the interactions of Menotrophin was found.
Interfrence
Risks
Drug should not be given to Pregnant Mothers, and Neonates.If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.
Storage
IM Inj Store at room temperature, Below 25°C or in refrigerator. Do not Freeze. Protect from Sunlight.
Warnings
Menotrophin should not be given to the pregnant women and use cautiously in the breast-feeding women.
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