Dose: 3.6 mg/kg
Single Dose: 3.6 (3.6)
Frequency: As recommended.
Route: IM
Instructions: Once in 3 days

. It is of Synthetic origin and belongs to Melarsen Oxide. It belongs to Pyruvate Kinase inhibitor pharmacological group on the basis of mechanism of action and also classified in Antiprotozal Agent pharmacological group.The Molecular Weight of Melarsoprol is 398.30.

Melarsoprol is contraindicated in conditions like Viral infection.

The severe or irreversible adverse effects of Melarsoprol, which give rise to further complications include Liver damage, Jarisch herxheimer reaction, Jaundice, Jaundice, Thrombophlebitis, Erythema, Coma, Albuminuria, Urinary casts.Melarsoprol produces potentially life-threatening effects which include Agranulocytosis, Thrombocytopenia, Aplastic Anemia, Encephalopathy, Exfoliative dermatitis, Aplastic anemia, Peripheral neuropathy. which are responsible for the discontinuation of Melarsoprol therapy.The symptomatic adverse reactions produced by Melarsoprol are more or less tolerable and if they become severe, they can be treated symptomatically, these include Headache, Fever, Abdominal pain, Urticaria, Arthralgia, Nausea and vomiting, Slurred speech, Erythematous rash, Abdominal colic, Convulsions, Limb pain, Erythematous rash.

Melarsoprol is primarily indicated in conditions like Trypanosomiasis.

No data regarding the interactions of Melarsoprol was found.

Drug should not be given to Pregnant Mothers, patients suffering from Kidney dysfunction, and patients suffering from Liver Malfunction.If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.

Melarsoprol should be used with extreme caution in patients with glucose-6-phosphate dehydrogenase (G-6-PD) deficiency. It should not be administered during epidemics of influenza. Malaria or pneumonia should be treated before administration of melarsoprol. Patient should be in hospital when they are treated with melarsoprol. It should be used with caution during pregnancy.