Dose: 0.178 to 0.714 mg/kg
Single Dose: 0.45 (0.446)
Frequency: 24 hourly
Route: PO
Instructions: -

Dose:
Single Dose:
Frequency:
Route:
Instructions: Not recommended in this age group

Dose:
Single Dose:
Frequency:
Route:
Instructions: Not recommended in this age group

. It is of Synthetic origin and belongs to Benze Disulfonamide. It belongs to NaCl cotransport inhibitor pharmacological group on the basis of mechanism of action and also classified in Diuretic Thiazide pharmacological group.The Molecular Weight of Mefruside is 382.90. Its pKa is 9.5.

'Mefruside is contraindicated in conditions like Hypercalcaemia,Addison''s disease,Hypersensitivity.'

The severe or irreversible adverse effects of Mefruside, which give rise to further complications include Hyperuricemia, Impaired glucose tolerance, Acute gout.Mefruside produces potentially life-threatening effects which include Hypokalemia, Hypokalemia. which are responsible for the discontinuation of Mefruside therapy.The signs and symptoms that are produced after the acute overdosage of Mefruside include Coma, Lethargy, CNS depression.The symptomatic adverse reactions produced by Mefruside are more or less tolerable and if they become severe, they can be treated symptomatically, these include Dyspepsia, Increased intracranial pressure, Hypovolemia, Acute urinary retention, dyspepsia.

Mefruside is primarily indicated in conditions like Edema, Hypertension, Oedema.

No data regarding the interactions of Mefruside was found.

Drug should not be given to Paediatrics, Pregnant Mothers, patients suffering from Kidney dysfunction, patients suffering from Liver Malfunction, and Neonates.If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.