Medazepam

Medazepam is a benzodiazepine similar to diazepam but less anticonvulsant activity. Medazepam is used in the treatment of anxiety.


Adult Dose
Dose: 10 to 20 mg
Single Dose: 15 (15)
Frequency: 24 hourly
Route: PO
Instructions: Usually in divided doses. Max dose 60 mg/day.
Neonatal
Paedriatic
Characteristics
. It is of Synthetic origin and belongs to Benzodiazepine. It belongs to Chloride Channel Potentiater (GABA operated) pharmacological group on the basis of mechanism of action and also classified in Sedatives and Hypnotics and Benzodiazepine pharmacological group.The Molecular Weight of Medazepam is 270.80. Its pKa is 6.2.
Contraindications
Medazepam is contraindicated in conditions like Depression,Myasthenia gravis,Respiratory insufficiency,Sleep apnea syndrome.
Effects
The signs and symptoms that are produced after the acute overdosage of Medazepam include Respiratory arrest.The symptomatic adverse reactions produced by Medazepam are more or less tolerable and if they become severe, they can be treated symptomatically, these include Sleepiness, Drowsiness, Fatigue, Pruritus, Skin eruptions, Paradoxical effects, Muscular hypotonia, Anterograde amnesia.
Indications
Medazepam is primarily indicated in conditions like Anxiety, Insomnia, Muscular contractures, and can also be given in adjunctive therapy as an alternative drug of choice in Alcohol withdrawal, Behavioural disorders, Depression, Epilepsy.
Interactions
No data regarding the interactions of Medazepam was found.
Interfrence
Risks
Drug should not be given to Pregnant Mothers, patients suffering from Kidney dysfunction, patients suffering from Liver Malfunction, and Neonates.If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.
Storage
Warnings
No data regarding the Warnings/Precuations of Medazepam is available.
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