Mebhydrolin

Mebhydrolin is a sedative anti-histamine with anti-muscarinic properties. Mebhydrolin is used for the symptomatic relief of allergic conditions including urticaria, rhinitis and, in pruritic skin disorders.


Adult Dose
Dose: 50 to 100 mg
Single Dose: 75 (75)
Frequency: 8 hourly
Route: PO
Instructions:
Neonatal
Dose: 6.25 mg/kg
Single Dose: 6.2 (6.25)
Frequency: 12 hourly
Route: Oral
Instructions:
Paedriatic
Dose: 5 mg/kg
Single Dose: 5 (5)
Frequency: 8 hourly
Route: Oral
Instructions: -
Characteristics
belongs to Methyl Carboline. It belongs to H1-antagonist pharmacological group on the basis of mechanism of action. The Molecular Weight of Mebhydrolin is 276.40. Its pKa is 6.7.
Contraindications
Mebhydrolin is contraindicated in conditions like Prostatic hypertrophy,Narrow-angle glaucoma,Hypersensitivity to any component of product.
Effects
The severe or irreversible adverse effects of Mebhydrolin, which give rise to further complications include Granulocytopenia, Neutropenia, Agranulocytosis.Mebhydrolin produces potentially life-threatening effects which include Blood dyscrasias. which are responsible for the discontinuation of Mebhydrolin therapy.The symptomatic adverse reactions produced by Mebhydrolin are more or less tolerable and if they become severe, they can be treated symptomatically, these include Sleepiness, Drowsiness.
Indications
Mebhydrolin is primarily indicated in conditions like Allergy, Angioedema, Angiooedema, Eczema, Hay fever, Pruritus, Rhinitis, Urticaria.
Interactions
No data regarding the interactions of Mebhydrolin was found.
Interfrence
Detection of IgE antibodies for allergy diagnosis
Risks
Drug should not be given to Pregnant Mothers.If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.
Storage
Warnings
Patients should observed caution while driving or performing other tasks requiring alertness, because may cause drowsiness. Mebhydrolin should be used with caution in patients with liver impairment, dose should be reduced in patients with renal impairment.
Back to List

Any information that appears on this website page is provided for the purpose of general information. This website has been compiled in good faith by HMIS.Online. However, no guarantee is made as to the completeness, validity or accuracy of the information it contains.