ORGAMETRIL SYNOMETROL

Dose: 5 to 10 mg
Single Dose: 7.5 (7.5)
Frequency: 24 hourly
Route: PO
Instructions:

. It is of Synthetic origin and belongs to Steroid. It belongs to Progesterone agonist pharmacological group on the basis of mechanism of action and also classified in Sex Hormones and Contraceptive Oral pharmacological group.The Molecular Weight of Lynoestrenol is 284.40. Its pKa is not ionizable.

Lynoestrenol is contraindicated in conditions like Myocardial infarction,Pulmonary embolism,Vaginal bleeding,Hepatic disease,Cerebrovascular accident,Vascular disease,Deep vein thrombosis.

The signs and symptoms that are produced after the acute overdosage of Lynoestrenol include Nausea, Vomiting, Breast swelling, Mastalgia.The symptomatic adverse reactions produced by Lynoestrenol are more or less tolerable and if they become severe, they can be treated symptomatically, these include Nausea, Vomiting, Alopecia, Weight gain, Acne, Changes in libido, Hyperphagia, Breast tenderness, Irregular uterine bleeding, Vaginal secretion, Greasy hair, Reduce vaginal secretion.

Lynoestrenol is primarily indicated in conditions like Hormonal contraception, and can also be given in adjunctive therapy as an alternative drug of choice in Endometritis, Uterine bleeding.

No data regarding the interactions of Lynoestrenol was found.

Elevated ESR and Haematocrit Values Elevation of Serum Iron, Copper and Alkaline Phosphatase

Drug should not be given to Paediatrics, Pregnant Mothers, Cardiac / Hypertensive Patients, patients suffering from Kidney dysfunction, patients suffering from Liver Malfunction, Geriatrics, and Neonates.If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.

Protect from Sunlight.

Chloasma is occasionally seen during the use. Occasionally changes in parameters of liver function, carbohydrate metabolism and heamostatis may occur. The slight signs of the virilization ( such as acne and hirsutism) observed in some patient. Slighty incresed risk of some cardiovascular disorders has been reported. Some forms of severe depression, if likely to be exacerbated by sex steroids.