Lymecycline

Bacteriostatic antibiotic with actions, adverse effects, and interactions similar to tetracycline.


Adult Dose
Dose: 2.857 to 4.285 mg/kg
Single Dose: 3.6 (3.571)
Frequency: As recommended.
Route: IV
Instructions: As Required
Neonatal
Paedriatic
Characteristics
. It is of Synthetic origin and belongs to Lysine (Tetracycline). It belongs to Antibacterial (Proetin synthesis inhibitor) pharmacological group on the basis of mechanism of action and also classified in Antibiotics pharmacological group.The Molecular Weight of Lymecycline is 602.60. Its pKa is 9.7, 7.7.
Contraindications
Lymecycline is contraindicated in conditions like Systemic lupus erythematosus.
Effects
The severe or irreversible adverse effects of Lymecycline, which give rise to further complications include Increased blood urea nitrogen, Azotemia, Hyperphosphatemia, Acidosis, Azotemia.Lymecycline produces potentially life-threatening effects which include Anaphylaxis, Acute hepatic dysfunctioning. which are responsible for the discontinuation of Lymecycline therapy.The symptomatic adverse reactions produced by Lymecycline are more or less tolerable and if they become severe, they can be treated symptomatically, these include Headache, Nausea, Diarrhea, Stomatitis, Vaginitis, Photosensitivity, Glossitis, Increased intracranial pressure, Enamel hypoplasia, Stomach pain.
Indications
Lymecycline is primarily indicated in conditions like Acne vulgaris, Amoebiasis, Bacterial infections, Brucellosis, Endocarditis, Ornithosis, Pneumonia, Psittacosis, Rickettsiae, Syphilis, and can also be given in adjunctive therapy as an alternative drug of choice in Acute sinusitis, Chronic bronchitis, Helicobacter pylori infection, Soft tissue infections, Trachoma.
Interactions
No data regarding the interactions of Lymecycline was found.
Interfrence
False Positive result of serum amylase in pregnant women False Positive fluorescence in Hengerty Method for measuring Urinary Catecholamines
Risks
Drug should not be given to Paediatrics, Pregnant Mothers, patients suffering from Kidney dysfunction, and Neonates.If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.
Storage
Caps Store Below 25°C. Protect from Sunlight.
Warnings
Tetracyclines should only be used with caution in patients with hepatic dysfunction, lest accumulation occurs with increased toxicity. Careful monitoring of dosage by serum levels is necessary. High dosage of tetracyclines may be hepatotoxic and great care should be used with concurrent administration of other hepatotoxic drugs. Tetracyclines should only be administered with great caution in patients with renal insufficiency lest accumulation occurs with increased toxicity. Dosage may require reduction. High dosage of tetracyclines may be nephrotoxic.
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