XYLOR XYLOR ALOR ALOR LOIN LOIN ALERTINE ALERTINE ALERTINE ALERFREE CELESTIN LORAGIX LOREFECT VICTRIN VICTRIN CLARIX CLARIX LORIN-NSA LORIN-NSA RESOTIN XALAR CONRAT CONRAT LORMAX FREND DINCLOR DINCLOR DINCLOR DINCLOR HISTADINE HISTADINE LORADINE LORADINE ZORDIN ZORDIN LORAZID LORAZID LORAZID FLORET FOZIL SENERGY-OD SENERGY-OD EZITINE EZITINE EZITINE TAVELOR TAVELOR TAVELOR CLARINASE REPETABS I-TADINE I-TADINE I-TADINE MAXOTEL MAXOTEL NONSED SELECTIN SELECTIN LOROKING LOROKING ALTEN CLINTOL ALLERGET ALLERGET NEUTIA TIRLOR TELDRIN NOCONGEST SINEASE SINEASE LATADINE OBSODINE MASTAL PLUS MASTAL MASTAL LORATODIX LORATODIX EXIGENTIN EXIGENTIN LEKSUS LEKSUS RHILOR D LOTIN LOTIN RHILOR RHILOR RHILOR LOHIST LOSAD LOSAD LOSAD LORATEL LORATEL LORIP LORIP ZEALON ZEALON URTI-CARE TEXCOL ALLERGY TEXCOL ALLERGY BACLOR LORATE ANTIAL ANTIAL P-SUR TELKOT TELKOT LORTIN-P LORTIN LORTIN-D ANTIMIN ANTIMIN ZESTRESS ZESTRESS HEISIL HEISIL LORID LORID PETAL PLUS LOREL LOREL HISTANIL HISTANIL HISTANIL ZORAT ALLERWOOD ALLERWOOD ALLERWOOD VIO-DINE VIO DINE PLUS VIO CID TALERGIN-P TALERGIN TALERGIN TALERGIN SOFTIN SOFTIN SOFTIN-P KORAT L-DIEN LIRIS LIRIS LORATINE LORATINE LORANEES DELTADIN HICO-OD RORAL RORAL ALLORAT ALLORAT RHINAMIN MEDIHIST LOD LOD LOD ALERSAP ZARIDINE LORDIN LORDIN SEMENOL CAPELLA RELENT ELEGON LORATAGEN LORATAGEN NOTRES LORESTIN LORESTIN CLARIDINE LUMFORT LUMFORT LORATAMED LORATAMED LORATAMED SEDINOR LARAIB LORACENT P-LOR LORATASCOT LORATASCOT JADE JADE ALERDE ALERDE HISTORAT ATADINE FESTAHIST HISPAR LEXIDEX LEXIDEX LOTAD LOLEGIN QURITIN REGLIN REGLIN QULOR MEGALOR VERAT LORTEC ALGAC CLAZIN ALGECARE ALGECARE LORYAN HISTAR LOR-10 LOR LOR LORTAB LORTAB LORTAB LORICH LORICH LORICH LORNAS LOW-H LOW-H ALFALOR RELIZIN ALORAN ALDINE CURATIDINE CLARIN HISTAMAC HISTAMAC HISTA HISTA POLENOR LORTAMINE SYNADIN SYNADIN ANTI- SNEEZE ANTI- SNEEZE ABROTIN ABROTIN ABROTIN ERATA SHAMIN RATAMAK ENKORET LORGY MEDILORIN MEDILORIN MEDILORIN LORATACARE ADIN ADIN LORATED CARA-GIX CARA-GIX LOLERGY LOLERGY MOMTEK LARGI LORATUS LORATUS AMBOZIAL AMBOZIAL LORATADVAN LORAMED LORAMED HISTAWEL HISROL LOINE LOINE LOINE LORALION LORALION L ION LORWIN ALERAWAY LORATOP DINSAVE AXALOR

Dose: 10 to 0 mg
Single Dose: 5 (5)
Frequency: 24 hourly
Route: PO
Instructions:

Dose: 5 mg/kg
Single Dose: 5 (5)
Frequency: 24 hourly
Route: Oral
Instructions: Dose for 2-7 Yrs of Children

. It is of Synthetic origin and belongs to Piperidine carboxylate. It belongs to H1-antagonist pharmacological group on the basis of mechanism of action. The Molecular Weight of Loratadine is 382.88. Its pKa is 5.0.

Loratadine is contraindicated in conditions like Hypersensitivity.

The severe or irreversible adverse effects of Loratadine, which give rise to further complications include Sinus tachycardia, Hair loss, Tinnitus, Hypotension, Insomnia, Blood dyscrasias, Tremors.Loratadine produces potentially life-threatening effects which include QT prolongation. which are responsible for the discontinuation of Loratadine therapy.The signs and symptoms that are produced after the acute overdosage of Loratadine include Hypotension, Nausea, Vomiting, Tachycardia, Convulsions, Drowsiness, Hallucinations, Ataxia, Hyperpyrexia, Tremor, Ventricular arrhythmias, Psychosis.The symptomatic adverse reactions produced by Loratadine are more or less tolerable and if they become severe, they can be treated symptomatically, these include Dizziness, Headache, Drowsiness, Fatigue, Nausea, Vomiting, Diarrhea, Constipation, Dry mouth, Pruritus, Sedation, Epigastric pain, gastric reflux.

Loratadine is primarily indicated in conditions like Chronic urticaria, Hay fever, NSAID associated ulceration, Perennial rhinitis, Seasonal allergic rhinitis, Skin allergies, Symptomatic relief of allergy.

Loratadine is known to interact with other drugs, the details of drug interactions is as follows:DrugDetailsSeverityOnsetManagementAmprenavirAmiprenavir possibly increases plasma concentration of Loratidine.Cimetidine (HCl)ClarithromycinClarithromycin increases the plasma concentration of loratadine by inhibiting its hepatic metabolism thus increases its plasma level upto 40%.MinorClosely monitor the patient for response and tolerance. Azithromycin and dirithromycin is considered as safer alternative.ErythromycinErythromycin increases the plasma concentration of loratadine by inhibiting its hepatic metabolism thus increases its plasma level upto 40%MinorClosely monitor the patient for response and tolerance. Azithromycin and dirithromycin is considered as safer alternative.FluconazoleFluconazole increases the AUC upto 180% for loratadine and upto 56%for its active metabolite by inhibiting its metabolism. MinorLoratadine considered as safer drug for use with fluconazole.Fluoxetine (HCl)Fluoxetine (HCl) inhibit metabolism of loratidineKetoconazoleKetoconazole inhibit the metabolism of Loratadine and increases the AUC upto 180% of loratadine and 56% for its metabolites due to inhibition of hepatic enzyme.MinorThis combination is considered safer to use.ProcarbazineQuinidine These interactions are sometimes beneficial and sometimes may pose threats to life. Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.

Drug should not be given to Pregnant Mothers, and Neonates.If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.

syrup Store Between 15°C-30°C. Protect from Sunlight and Heat.

Loratadine should be used with caution in patients with history of heart disease, thyroid disease, kidney disease, liver disease, breathing problems or if have any allergy. It should be used with caution during pregnancy or lactation.