Ivermectin

Ivermectin is anthelmintic agent. Ivermectin is a semisynthetic macrocyclic lactone. Ivermectin is a mixture of two closely related it compound B1a and B1b. Ivermectin is derived from the soil actinomycete Streptomyces avermitilis and effective against many nematodes and arthropod species.

Brands
IVERTERM MACTOVIN ODIVER ODIVER MECTIS STIVER IVERMITE MECTIMITE IVERATAN IVERLEX IVERMEC SCABIMAC VECTIN SCABI-MECT
Adult Dose
Dose: 200 ug/kg
Single Dose: 200 (200)
Frequency: 24 hourly
Route: PO
Instructions: For 2 Consecutive Days
Neonatal
Dose:
Single Dose:
Frequency:
Route:
Instructions: Not recommended in this age group
Paedriatic
Dose:
Single Dose:
Frequency:
Route:
Instructions: Not recommended in this age group
Characteristics
. It is of Semi Synthetic origin and belongs to Macrocyclic lactone. It belongs to Anthelmintics pharmacological group.The Molecular Weight of Ivermectin is 875.10.
Contraindications
Ivermectin is contraindicated in conditions like Meningitis,Hypersensitivity,Trypanosomiasis,Seizures.
Effects
The signs and symptoms that are produced after the acute overdosage of Ivermectin include Emesis, Mydriasis, Sedation.The symptomatic adverse reactions produced by Ivermectin are more or less tolerable and if they become severe, they can be treated symptomatically, these include Dizziness, Headache, Nausea, Diarrhea, Fever, Myalgia, Rashes, Pruritus, Cough, Arthralgia, Edema, Orthostatic hypotension, Sore throat, Lymphadenopathy, Lymph-node tenderness, dizziness.
Indications
Ivermectin is primarily indicated in conditions like Lymphatic filariasis, Onchoceriasis, Strongyloides stercoralis, Strongyloidiasis.
Interactions
No data regarding the interactions of Ivermectin was found.
Interfrence
Elevation in ALT or AST
Risks
Drug should not be given to Paediatrics, Pregnant Mothers, and Neonates.If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.
Storage
Warnings
Ivermectin should not be used in the pregnant or the breast feeding women or children
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