ELANTAN ELANTAN ELANTAN LONG IMDUR CORLET CORLET MONIS MONIS MONIS MONIS MONIS MONIS-XR MONIS-XR VASOCORD VASOCORD VASOCORD VASOCORD ISMO 20 FLO MONOTRATE MONOTRATE SORBIMON SORBIMON MONO CARD UNITRATE ISOTIME-20 SAVDIL SAVDIL SAVDIL ISOMON ISOTRATE ISOTRATE ISOTRATE ISOTRATE ISOTRATE MONIT-20 SEQUENCE SEQUENCE ISOTIME-60 MONOSOR MONOSOR MONOSOR XL ISOTAB ISOTAB MONOSORBID MONOSORBID MONOTAB MONOTAB ANGINIL ANGINIL ISOTAB-XR ISODIL ISODIL ISODIL ISODIL ISODIL ISODIL

Dose: 20 to 60 mg
Single Dose: 40 (40)
Frequency: 24 hourly
Route: PO
Instructions:

Dose:
Single Dose:
Frequency:
Route:
Instructions: Not recommended in this age group

Dose:
Single Dose:
Frequency:
Route:
Instructions: Not recommended in this age group

Isosorbide 5-Mononitrate also known as Isorbide, Isorbide, Isorbide, Isorbide, Isorbide. . It is of Synthetic origin and belongs to Nitrates. It belongs to EDRF (NO) agonist pharmacological group on the basis of mechanism of action and also classified in Antianginal Agents and Vasodilators pharmacological group.The Molecular Weight of Isosorbide 5-Mononitrate is 191.10.

Isosorbide 5-Mononitrate is contraindicated in conditions like Glucoma,Cardiogenic shock,Obstructive cardiomyopathy,Constrictive pericarditis,Low cardiac filling pressure,Hypersensitivity,Raised intracranial pressure,Aortic stenosis,Mitral stenosis,Acute circulatory failure,Severe hypotension,Pericardiac tamponade,Arterial hypoxemia,Orthostatic disturbance of circulatory regulation.

The severe or irreversible adverse effects of Isosorbide 5-Mononitrate, which give rise to further complications include Hypotension, Hypotension, Orthostatic hypotension, Collapse, Decreased cardiac output, Paradoxical bradycardia.The signs and symptoms that are produced after the acute overdosage of Isosorbide 5-Mononitrate include Hypotension, Tachycardia, Confusion, Palpitations, Headache, Syncope, Neurologic deficit, Increased intracranial pressure, Flushed skin.The symptomatic adverse reactions produced by Isosorbide 5-Mononitrate are more or less tolerable and if they become severe, they can be treated symptomatically, these include Weakness, Dizziness, Vertigo, Headache, Nausea, Vomiting, Myalgia, Palpitation, Hypotension, Urinary incontinence, Allergic skin reactions, Fecal incontinence, Orthostatic hypotension, Apprehension, dizziness, Weakness.

Isosorbide 5-Mononitrate is primarily indicated in conditions like Congestive heart failure, Prevention and treatment of scurvy, Prophylaxis of angina.

Isosorbide 5-Mononitrate is known to interact with other drugs, the details of drug interactions is as follows:DrugDetailsSeverityOnsetManagementAlcoholVORICONAZOLEVoriconazole may increase the serum concentration of isosorbide mononitrate by decreasing its metabolism. Monitor for changes in the therapeutic and adverse effects These interactions are sometimes beneficial and sometimes may pose threats to life. Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.

False decrease in serum cholestrol in Zlotkis-Zak Colour reaction Increases the Urinary conc. of Catecholamines and its metabolites

Drug should not be given to Paediatrics, Pregnant Mothers, Geriatrics, and Neonates.If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.

Tab Store in a well closed container, at room temperature, Below 30°C or in refrigerator. Do not Freeze.

Excessive use of isosorbide 5-mononitrate may cause headache, so reduce the dose and use analgesics (painkiller). In terminating treatment of angina, gradually reduced the dose in order to avoid withdrawal reactions. Extended-release isosorbide 5-mononitrate should be avoided in the patient with the GI disease such as the hypermotility or malabsorption syndrome, this dosage form may not be dissolved and may be excreted intact in these conditions. In making the decision to administer the drug during pregnancy, the potential risk to the fetus must be weighed against the potential benefits to the mother.