SAVENTRINE

Dose: 0.002 to 0.007 mg/kg
Single Dose: 0.0045 (0.0045)
Frequency: As recommended.
Route: Inhalation
Instructions: As Required

Dose: 0.1 to 4 ug/kg.min
Single Dose: 2 (2.05)
Frequency: As recommended.
Route: IV Infusion
Instructions: As required

Dose: 0.1 to 4 ug/kg.min
Single Dose: 2 (2.05)
Frequency: As recommended.
Route: IV Infusion
Instructions: For Paeds of All Ages , As Required

Isoproterenol also known as Isoprenaline, Isoprenaline. Isoproterenol (HCl), Isoproterenol (HCl) are the derivatives of Isoproterenol. It is of Synthetic origin and belongs to Catecholamine. It belongs to Beta adrenergic agonist pharmacological group on the basis of mechanism of action and also classified in Bronchodilator pharmacological group.The Molecular Weight of Isoproterenol is 211.30. Its pKa is 8.64.

Isoproterenol is contraindicated in conditions like Cardiac arrhythmia,Diabetes mellitus,Myocardial infarction,Thyrotoxicosis,Ischaemic heart disease,Cystic fibrosis,Subvalvular aortic stenosis,Hypersensitivity,Quadriplegia.

The severe or irreversible adverse effects of Isoproterenol, which give rise to further complications include Cardiac arrhythmias, Cardiac arrhythmias, Dizziness, Cough, Nervousness, Tremors.Isoproterenol produces potentially life-threatening effects which include Cardiac Arrest, Cardiac arrest, Ventilatory arrest. which are responsible for the discontinuation of Isoproterenol therapy.The signs and symptoms that are produced after the acute overdosage of Isoproterenol include Tachycardia, Tremor, Restlessness, Anxiety, B.P. alteration, Excitement.The symptomatic adverse reactions produced by Isoproterenol are more or less tolerable and if they become severe, they can be treated symptomatically, these include Dizziness, Headache, Nausea, Palpitation, Tachycardia, Nervousness, Irregular heart beat, Dryness of mouth, Sleeplessness, Flushing, Tremor, Chest pain, Hypertension, Anginal pain, nervousness, Nervousness, dizziness, damage to the teeth.

Isoproterenol is primarily indicated in conditions like Acute bronchospasm, Asthma, Bradycardia, Bronchitis, Heart block, Reversible airways obstruction, Stokes-adams attack.

Isoproterenol is known to interact with other drugs, the details of drug interactions is as follows:DrugDetailsSeverityOnsetManagementAdrenalineAmitriptyline (HCl)Bretylium (Tosylate)Bretylium may increase effects of Isoproterenol.EnfluraneHalothaneLevodopaMilrinone (Lactate)Propranolol (HCl)Propranolol(HCl) may blunt ionotropic response.SevofluraneTheophylline These interactions are sometimes beneficial and sometimes may pose threats to life. Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.

Drug should not be given to Paediatrics, Pregnant Mothers, and Neonates.If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.

Tab, Inj Store Below 25°C.

Isoproterenol should be used with special caution in patients with ischaemic heart disease, diabetes mellitus, pheochromocytoma or hyperthyroidism. Avoid prolong, sublingual use, as it cause sever damage to the teeth. The drug should be given with extreme caution in the patient with severe or uncontrolled hypertension. Isoproterenol should be used in pregnancy and lactation only when clearly needed.