Isoetharine

Isoetharine is a bronchodialator.It works by relaxing muscles in airways to improve breathing.


Brands
Adult Dose
Dose: 0.005 to 0.09 mg/kg
Single Dose: 0.048 (0.0475)
Frequency: 4 hourly
Route: Inhalation
Instructions: -
Neonatal
Paedriatic
Dose: Doses not established for this age group
Single Dose:
Frequency:
Route:
Instructions:
Characteristics
Isoetharine also known as Ispetarine. . It is of Synthetic origin and belongs to Catecholamine. It belongs to Beta-2 adrenergic agonist pharmacological group on the basis of mechanism of action and also classified in Bronchodilator pharmacological group.The Molecular Weight of Isoetharine is 239.30.
Contraindications
Isoetharine is contraindicated in conditions like Cardiac arrhythmia,Hypertension,Myocardial infarction,Thyrotoxicosis,Ischaemic heart disease,Subvalvular aortic stenosis,Hypersensitivity.
Effects
The severe or irreversible adverse effects of Isoetharine, which give rise to further complications include Tachycardia, Palpitation, Headache, Extrasystoles, Intolerable muscle tremors, Breathing difficulty.Isoetharine produces potentially life-threatening effects which include Cardiac Arrest, Ventilatory arrest. which are responsible for the discontinuation of Isoetharine therapy.The signs and symptoms that are produced after the acute overdosage of Isoetharine include Nausea, Tachycardia, Dry mouth, Headache, Tremor, Restlessness, Anxiety, B.P. alteration, Excitement.The symptomatic adverse reactions produced by Isoetharine are more or less tolerable and if they become severe, they can be treated symptomatically, these include Weakness, Dizziness, Nausea, Vomiting, Palpitation, Insomnia, Irregular heart beat, Chest pain, Increase in heart rate.
Indications
Isoetharine is primarily indicated in conditions like Acute bronchospasm, Asthma, Asthmatic bronchitis, Bronchitis, Chronic obstructive pulmonary disease, Emphysema.
Interactions
No data regarding the interactions of Isoetharine was found.
Interfrence
Risks
Drug should not be given to Pregnant Mothers, patients suffering from Kidney dysfunction, patients suffering from Liver Malfunction, and Neonates.If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.
Storage
Inhaler Store Below 40°C. Protect from Sunlight and Heat.
Warnings
Avoid intraneural or intravascular injection of isoetharine. Avoid situations that may trigger asthmatic attacks such as smoking,dry air etc The drug should be used with caution in the patient with cardiac diseases, AV block associated with digoxin toxicity, narrow-angle glaucoma, shock, during general anesthesia with halogenated agents or cyclopropane, diabetes and in psychoneurotic individuals.
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