Iodine Compounds

Iodine and iodine releasing agents are widely used as topical broad spectrm antiseptics and as disinfectant and sanitizers. Elemental iodine was discovered in 1811 and is ablack blue material. Elemental iodine is highly irritant and corrosive but formulation as an iodophor greatly reduces these unwanted adveres effects.

Brands
Adult Dose
Dose: 10%
Single Dose: 10 (10)
Frequency: As recommended.
Route: Topical
Instructions: As required
Neonatal
Paedriatic
Characteristics
. It is of Natural origin and belongs to Iodides. It belongs to Dermatological-Antiseptic pharmacological group on the basis of mechanism of action and also classified in Antiseptics and Germicides and Counter Irritant pharmacological group.The Molecular Weight of Iodine Compounds is 253.80. Its pKa is 0.75.
Contraindications
Iodine Compounds is contraindicated in conditions like Conception,Local sensitization.
Effects
The severe or irreversible adverse effects of Iodine Compounds, which give rise to further complications include Gi bleeding, Infant hypothyroidism, Goitre, Thyroid adenoma, Iodism.Iodine Compounds produces potentially life-threatening effects which include Neutropenia. which are responsible for the discontinuation of Iodine Compounds therapy.The signs and symptoms that are produced after the acute overdosage of Iodine Compounds include Diarrhea, Abdominal pain, Circulatory failure, Nausea & vomiting, Thirst, Purging.The symptomatic adverse reactions produced by Iodine Compounds are more or less tolerable and if they become severe, they can be treated symptomatically, these include Fever, Skin rashes, Confusion, Joint pain, Slivary gland swelling, Staining of skin & clothes.
Indications
Iodine Compounds is primarily indicated in conditions like Acne vulgaris, Bladder irrigation, Burns, Hyperthyroidism, Incisions, Minor injuries, Pharyngitis, Skin infections, Stomatitis, Thyroid gland radiation protection, Thyroid involution, Ulcers, Vaginal infections.
Interactions
No data regarding the interactions of Iodine Compounds was found.
Interfrence
Thyroid Funtion Test
Risks
Drug should not be given to Pregnant Mothers, and Neonates.If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.
Storage
Tincture, Oint, Cream, Gargle, Dry Powder Sprays, Vag suppositories, Vag Gel Store in a well closed container. Protect from Sunlight.
Warnings
Caution is necessary if preparations containing iodine or iodides are taken for prolong periods and such preparation should not be taken regularly during pregnancy except when iodine supplementation is required. Iodine should not be given to the nursing mother and caution is also required when given to the children. Patients over the age of 45 years or with nodular goitres are specially susceptible to hyperthyroidism. Solution of iodine applied to the skin should not be covered with occlusive dressing . It should be used with caution in patient with cardiac disease or renal (kidney) impairment.
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