Indoramin (HCl)

Indoramin (HCl) is a receptor blocking agent. Chemically Indoramin (HCl) is identified as N-[ 1-[2-(1H-indol-3-yl) ethyl ]-4-piperidinyl] benzamide. It produces relaxation of blood vessels and lowers blood pressure. Indoramin (HCl) is used in hypertension and in prophylaxis of migraine. Indoramin (HCl) is prepared by chemical synthesis. Indoramin (HCl) is not available in any combiantion preparations. Indoramin (HCl) is administered orally.

Brands
Adult Dose
Dose: 0.357 to 1.428 mg/kg
Single Dose: 0.89 (0.8925)
Frequency: 12 hourly
Route: PO
Instructions: -
Neonatal
Paedriatic
Characteristics
. It is of Synthetic origin and belongs to Indole. It belongs to Alpha-1 adrenergic antagonist pharmacological group on the basis of mechanism of action and also classified in Antihypertensive Agents pharmacological group.The Molecular Weight of Indoramin (HCl) is 383.90. Its pKa is 7.8.
Contraindications
Indoramin (HCl) is contraindicated in conditions like Cardiac failure.
Effects
The signs and symptoms that are produced after the acute overdosage of Indoramin (HCl) include Hypotension, Convulsions, Coma, Unconsciousness, Respiratory depression, Hypothermia, Fits.The symptomatic adverse reactions produced by Indoramin (HCl) are more or less tolerable and if they become severe, they can be treated symptomatically, these include Dizziness, Headache, Fatigue, Dry mouth, Sedation, Nasal stiffiness, Depression, Weight gain, Failure of ejaculation, Dry mouth, dizziness.
Indications
Indoramin (HCl) is primarily indicated in conditions like Benign prostatic hyperplasia, Hypertension, Infertility or irregular cycles, Migraine prophylaxis, and can also be given in adjunctive therapy as an alternative drug of choice in Urinary outflow obstruction.
Interactions
No data regarding the interactions of Indoramin (HCl) was found.
Interfrence
Risks
Drug should not be given to Paediatrics, Pregnant Mothers, patients suffering from Kidney dysfunction, patients suffering from Liver Malfunction, and Neonates.If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.
Storage
Tab Store Below 25°C. Protect from Sunlight.
Warnings
Patients should observe caution while driving or performing other tasks requiring alertness, because it may cause drowsiness. Indoramin should be used with caution in patients with hepatic (liver), kidney insufficiency, epilepsy, parkinson s disease or history of depression. It should be avoided in pateints with heart failure.
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