IFEN IFEN IFEN DOLOFEN RUMAFEN RUMAFEN BOSCHOFEN BOSCHOFEN PABROFEN PANGO PANGO PANGO PANGO EPROFEN EPROFEN EPROFEN EPROFEN IBU-SLOW PEDIFEN PEDIFEN PROFEN PROFEN PROFEN PROFEN PROFEN PROFEN FUFEN FUFEN FUFEN FUFEN HIZOFEN HIZOFEN HUGON IODOFEN IODOFEN IODOFEN IODOFEN IODOFEN JAEFEN JAEFEN JAEFEN JAEFEN JAEFEN JAEFEN KAYFEN KAYFEN RUMATOFEN RUMATOFEN RUMATOFEN RUMATOFEN RUMATOFEN ARINAC ARINAC BRUFEN BRUFEN BRUFEN BRUFEN BRUFEN BRUFEN BRUFEN BRUFEN BRUFEN NOVOFEN NOVOFEN NOVOFEN NOVOFEN NOVOFEN NOVOFEN NOVOFEN NOVOFEN OFEN OFEN OFEN MACPROFEN MACPROFEN MACPROFEN MACPROFEN MACPROFEN MACPROFEN MACPROFEN IBUFIN IBUFIN IBUFIN IBUFIN MEDFEN IBUPROFEN IBUPROFEN IBUPROFEN IBUPROFEN IBUMID IBUMID IBUMID IBUMID PHARFEN PHARFEN PHARFEN PHARFEN PHARFEN PHARFEN PROMIN PROMIN PROMIN PROMIN RAPIFEN INZEL TEXCOL SINUS TEXCOL SINUS SEMORFEN SEMORFEN SEMORFEN SEMORFEN IBUPROFEN IBUPROFEN IBUPROFEN INFLAM INFLAM INFLAM INFLAM INFLAM BLUDOL BLUDOL BLUDOL TAGAFIN TAGAFIN IBU IBU IBU IBU IBU IBU RUBERIN RUBERIN ZEFEN ZEFEN ZEFEN ZEFEN IBUPROFEN IBUPROFEN IBUPROFEN IBUPROFEN ANGLOFEN ANGLOFEN AKSOFEN AKSOFEN IBURIN IBURIN IBURIN IBURIN IBURIN IBUPROFEN IBUPROFEN IBUPROFEN IBU-GESIC NEO-BUTINAL NEO-BUTINAL NEO-BUTINAL NEO-BUTINAL PROSTA KARBUFEN KARBUFEN KARBUFEN KARBUFEN KARBUFEN IBUPROFEN IBUPROFEN IBUPROFEN TRUE-FEN TRUE-FEN TRUE-FEN TRUE-FEN WILFEN WILFEN WILFEN WILFEN WILFEN DORAFEN DORAFEN DORAFEN BRUFEDIN BRUFEDIN BRUFEDIN DELTAFEN DELTAFEN OCEFEN OCEFEN OCEFEN OCEFEN OCEFEN REXAPROFEN REXAPROFEN REXAPROFEN IBUGESIC IBUGESIC IBUGESIC IBUGESIC RUMIN RUMIN RUMIN RUMIN RUMIN MOTRIN PRUFO PRUFO PRUFO FEDRIN FEDRIN IBUGEN IBUGEN IBUGEN IBUGEN FERROFEN FERROFEN FERROFEN FERROFEN BRUNAC RUNIK RHINOFF LEMACH IMCOFEN MUFEN MUFEN MUFEN IBUCIL IBUCIL REGOFEN REGOFEN REGOFEN REGOFEN SAPROFEN MEDIBRU MEDIBRU REBUGEN AZOFIN AZOFIN AZOFIN IBUSER IBUSER IBUSER IBUSER WERRIDAL RHINOFF FORTE BRUFEN RETARD ARINAC FORTE AMROFEN AMROFEN PANIL PANIL PANIL ARUFEN RUNIK FORTE FEDRIN FORTE NEONAC IBUPROFEN IBUPROFEN MEGAFEN MEGAFEN MEGAFEN MEGAFEN KANFLAM BRUFED HIFEN HIFEN OTTOFEN OTTOFEN OTTOFEN OTTOFEN OTTOFEN ARINAC BLISTER DOLOCOL DOLOCOL DOLOCOL FORTE ARTIJESIC ARTIJESIC ARTIJESIC BAPROFEN BAPROFEN BAPROFEN BAPROFEN FLUREST RHENONILL FORTE NEOPROFEN NEOPROFEN NEOPROFEN NEUPROFEN OFCIN COLDTHRO EUROFEN EUROFEN BEFEN RUMAT RUMAT RESFEN RESFEN RESFEN RESFEN RESFEN PAEDIATRIC RESFEN PAEDIATRIC RESINAC RESINAC FORTE FRINAC GLARE SUS IGRAFEN BRAVOFEN BRAVOFEN UNIPROFEN UNIFEN AL-FEN AL-FEN AL-FEN SEDOFEN-FORTE SEDOFEN-P ZINTAFEN ZINTAFEN SUDOFIN SUDOFIN WEFEN FENOBER FENOBER FENOBER FENOBER IBOFEN IBOFEN IBOFEN PHINE XIBEN FAST/ SLOW XIBEN IBUGRAY IBUGRAY FENFLEX REMOFEN REMOFEN REMOFEN MB-FEN MB-FEN IBUPROFEN CAYPROF PYROFEN PYROFEN PYROFEN PYROFEN PYROFEN SINURINE FORTE SINURINE FORTE IBUPED ISEN RIBUFEN EXIFIN FENBRO HEBOFEN HEBOFEN IBOWIN IBOWIN IBULEXIN IBULEXIN IBUPULSE IBURFEN IBUSOFT IBUSOFT PAINCARE PAINCARE PAINCARE ZUFEN ZUFEN ZUFEN ZUFEN ZUFEN IBURIN PLUS BRUFEN PLUS AMOFEN BIOSOFT REDUCE ACHE PROPEN VEE BUFEN VEE BUFEN VEE BUFEN SYNOFEN BRUGESIC UNIPROFIN EVERFEN EVERFEN EVERFEN BIOFEN IBUCARE IBUPROS IBUPROS IBUPROS IBUPROS TESCO TESCO TESCO TESCO CARUFEN CARUFEN APRO TABLET PESUDOMOL PESUDOMOL FORT PESUDOMOL FORT IBUNOL BUMEX ENAC MEDIBRRUFEN MEDIBRUFEN MEDIBRUFEN MEDIBRUFEN MEDIBRUFEN PREXOL PROPHED PROPHED FORTE PROPHED FORTE STABRU BLUFEN BROSUN FLUMAX IBU-U MICAFEN NENFEN NENFEN NENFEN PIRONEC PIRONEC PLUS Q-FEN ROVINAC ROVINAC VARINAC ZAYFEN ACTIFEN ACTIFEN ACTIFEN ACTIFEN ROVINAC FORTE FYNKOBEN GLOPROFIN HIBTOL HIBTOL IBOZ AMBROFEN AMBROFEN AMBROFEN AMBROFEN AMBROFEN AMBROFEN AMBROFEN B-FEN B-FEN BEPOFEN BEPOFEN BEPOFEN BRUCAM IBUCARE IBUPROFEN SUPROFEN SUPROFEN TABALON TABALON TABALON ONYFEN IBUQUIK IBUQUIK IBUQUIK IBUQUIK RHUNOR REDUCE ACHE FORTE KEFENTECH IBUSIM Proflam ZEFRIN

Dose: 200 to 600 mg
Single Dose: 400 (400)
Frequency: 8 hourly
Route: PO
Instructions: Maximum dose 1.2 g

Dose: 5 to 10 mg/kg
Single Dose: 7.5 (7.5)
Frequency: 8 hourly
Route: Oral
Instructions: Maximum dose: 40 mg/kg

. It is of Synthetic origin and belongs to Propionic Acid. It belongs to Cyclo-oxygenase inhibitor pharmacological group on the basis of mechanism of action and also classified in Analgesics and Anti-inflammatory Agents and NSAIDs pharmacological group.The Molecular Weight of Ibuprofen is 206.30. Its pKa is 4.4, 5.2.

Ibuprofen is contraindicated in conditions like Hypertension,Peptic ulcer,Bronchospasm,Renal failure,Hypersensitivity,GI bleeding.

The severe or irreversible adverse effects of Ibuprofen, which give rise to further complications include Thrombocytopenia, Elevated blood pressure.Ibuprofen produces potentially life-threatening effects which include Vomiting, Peptic ulceration, Hematemesis, Severe gastric pain. which are responsible for the discontinuation of Ibuprofen therapy.The signs and symptoms that are produced after the acute overdosage of Ibuprofen include Hypotension, Nausea, Vomiting, Cardiac arrhythmias, Coma, Seizures, Acidosis, Ataxia, Headache, Renal failure, Epigastric pain, Hyperkalemia, GI bleeding, Renal and Hepatic dysfunction.The symptomatic adverse reactions produced by Ibuprofen are more or less tolerable and if they become severe, they can be treated symptomatically, these include Flatulence, Dizziness, Headache, Diarrhea, Constipation, Tinnitus, Blurred vision, Rashes, Urticaria, Pruritus, Gastritis, Depression, Elevation of liver enzymes, Fluid retention, Edema, SomnolenceX, Hearing loss, Hypersensitivity reactions, Blood dyscrasias, Angioedema, Vision disturbances, Aseptic maningitis, dizziness.

Ibuprofen is primarily indicated in conditions like Cystic fibrosis, Fever, Juvenile chronic arthritis, Migraine, Mild to moderate pain, Musculoskeletal pain, Nausea and vomiting (palliative care), Osteoarthritis, Pain, Post operative analgesia, Rheumatoid arthritis, Severe pain and tenderness in benign fibrocystic breast disease, Toothache, and can also be given in adjunctive therapy as an alternative drug of choice in Acute arthritis, Ankylosing spondylitis, Dysmenorrhoea, Inflammatory bowel disease.

Ibuprofen is known to interact with other drugs, the details of drug interactions is as follows:DrugDetailsSeverityOnsetManagementAescinAspirinIbuprofen bind reversibly at the active site of platelet cyclogenase and thus competitively inhibit this enzyme but because this binding is reversible so it cause temporary rather than sustained depression of thromboxane formation an thus antagonize the anti-platelet and cardioprotective effect of low-dose aspirin.MajorTake medication with food and immediately report sign and symptoms of GI ulceration and bleeding.ChlorthalidoneDesmopressin (Acetate)DiazoxideHypotensive effect of when diazoxide antagonised by Ibuprofen.Interferon BetaMethotrexateIbuprofen increases the plasma concentration of methotrexate by interfering with renal elimination results in increased toxicity and pharmacological effects.MajorClosely monitor for signs of bone marrow suppression and nephrotoxicity. Avoid any other over-the-counter NSAID product.MoclobemideOxaliplatinYou should inform your doctor before using this combination.Do not start or stop any medicine without doctor or pharmacist approval.PemetrexedIbuprofen (400 mg four times a day) can decrease the clearance of pemetrexed.Caution should be used when administering ibuprofen concurrently with Pemetrexedto patients with mild to moderate renal insufficiencyStreptomycinConcurrent use may cause toxicities to the kidneys.TorasemideIbuprofen, a strong CYP2C9 inhibitor, may increase the serum concentration of Torasemide, a CYP2C9 substrate, by decreasing Torasemide metabolism and clearance. Consider alternate therapy or monitor for changes in the therapeutic and adverse effects of Torasemide if Ibuprofen is initiated, discontinued or dose changed.VORICONAZOLEIbuprofen may increase the serum concentration of voriconazole by decreasing its metabolism. Monitor for changes in the therapeutic and adverse effects of voriconazole if ibuprofen is initiated, discontinued or dose changed.Vortioxetineeither increases effects of the other by serotoninmonitor closely These interactions are sometimes beneficial and sometimes may pose threats to life. Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.

Imparting a pinkishred to the urine

Drug should not be given to Neonates.If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.

Tab Store Below 40°C. Protect from Sunlight and Moisture.

Ibuprofen should be used with caution in patients with intrinsic coagulation defects and those on anticoagulant therapy. It should be used with caution in patients with compromised cardiac function, hypertension other condition predisposing to fluid retention. It should be used with extra care in the presence of existing uncontrolled infection. Perform periodic auditory (hearing) function test during chronic therapy. Discontinue drug if skin reaction occurred.