Human Anti-D Immunoglobulin

Human Anti-D Immunoglobulin is used to prevent a Rh-ve mother actively forming antibodies to fetal Rh+ve red blood cells that may pass into maternal circulation during childbirth, abortion or other sensitizing events.

Brands
Adult Dose
Dose: 7.143 to 21.429 IU/kg
Single Dose: 14 (14.286)
Frequency: As recommended.
Route: IM
Instructions: As Required
Neonatal
Paedriatic
Dose: 125 to 0 Units/kg
Single Dose: 62 (62.5)
Frequency: As recommended.
Route: Idtopathic theombocytopenic purpuron.
Instructions:
Characteristics
. It is of Natural origin. It belongs to Antibody pharmacological group on the basis of mechanism of action and also classified in CDC Biologicals and Immune Globulin pharmacological group.
Contraindications
Human Anti-D Immunoglobulin is contraindicated in conditions like Hypersensitivity to any component of product.
Effects
The severe or irreversible adverse effects of Human Anti-D Immunoglobulin, which give rise to further complications include Hemorrhage.Human Anti-D Immunoglobulin produces potentially life-threatening effects which include Anaphylactoid reactions, Hypotension, Collapse, Chest pain. which are responsible for the discontinuation of Human Anti-D Immunoglobulin therapy.The symptomatic adverse reactions produced by Human Anti-D Immunoglobulin are more or less tolerable and if they become severe, they can be treated symptomatically, these include Headache, Nausea, Chills, Flushing.
Indications
Human Anti-D Immunoglobulin is primarily indicated in conditions like Idiopathic thrombocytopenic purpura, Rhesus haemolytic disease.
Interactions
No data regarding the interactions of Human Anti-D Immunoglobulin was found.
Interfrence
Positive direct antiglobulin test
Risks
If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.
Storage
Inj Protect from Sunlight.
Warnings
Anti-D immunoglobulin should be administered with caution to Rh +ve person for the treatment of blood disorder.
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