Homatropine (HBr)

Homatropine (HBr) is the hydrobromide salt of homatropine which is atropine ester of mendelic acid, having anticholinergic effects similar to atropine but weaker than atropine. Homatropine (HBr) is used as a mydriatic. Homatropine (HBr) is relaxes the eye muscles and causing the pupil to dilate. italso used during eye examinations.

Brands
HOMATROPINE
Adult Dose
Dose: 0.001 mg
Single Dose: 0.001 (0.001)
Frequency: As recommended.
Route: Ophthalmic
Instructions: As Required
Neonatal
Dose: 1 to 2 %
Single Dose: 1.5 (1.5)
Frequency: As recommended.
Route: Opthalmic
Instructions: As Required
Paedriatic
Dose: 1 to 0 %
Single Dose: 0.5 (0.5)
Frequency: 12 hourly
Route: Opthalmic
Instructions: Older children
Characteristics
. It is of Semi Synthetic origin and belongs to Tertiary Amine. It belongs to Cholinergic muscarinic antagonist pharmacological group on the basis of mechanism of action and also classified in Opthalmic Products and Mydriatic pharmacological group.The Molecular Weight of Homatropine (HBr) is 356.30. It is weakly acidic drug, 5.67% solution of the drug is isotonic and Its pKa is 9.9.
Contraindications
Homatropine (HBr) is contraindicated in conditions like Narrow-angle glaucoma.
Effects
The severe or irreversible adverse effects of Homatropine (HBr), which give rise to further complications include Posterior synechia.Homatropine (HBr) produces potentially life-threatening effects which include Coma, Convulsions, Respiratory Failure, Respiratory failure. which are responsible for the discontinuation of Homatropine (HBr) therapy.The symptomatic adverse reactions produced by Homatropine (HBr) are more or less tolerable and if they become severe, they can be treated symptomatically, these include Weakness, Dizziness, Headache, Drowsiness, Insomnia, Nervousness, Hypersensitivity reactions, Pain, Flushing, Contact dermatitis, Loss of taste, Lacrimation, Conjunctivitis, Brow ache, Photophobia, Bloated feeling, nervousness, Nervousness, dizziness.
Indications
Homatropine (HBr) is primarily indicated in conditions like Cycloplegia induction, Glucoma, Induce cycloplegia, Induce mydriasis, Mydriasis induction, Uveitis.
Interactions
No data regarding the interactions of Homatropine (HBr) was found.
Interfrence
Risks
Drug should not be given to Paediatrics, Geriatrics, patients suffering from Kidney dysfunction, patients suffering from Liver Malfunction, Neonates, and Pregnant Mothers.If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.
Storage
Eye Drops Store in a well closed container, Below 40°C. Do not Freeze.
Warnings
Homatropine should be used with caution in patients with glaucoma. Do not use this medication while wearing soft contact lenses because the lenses may be discolored. This medication should be used during pregnancy only if clearly needed.should be used with cuation in pateints with fever.
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