NITROLINGUAL NITRONAL NITRONAL NITRONAL DEPONIT DEPONIT ANGIOCARD ANGIOCARD ANGISED NITROMINT NITROMINT RETARD NITROMINT RETARD SUSCARD BUCCAL SUSCARD BUCCAL SUSTAC SUSTAC ANGINOR ANGILINGUAL ANGILINGUAL NITROSUST NITROSUST NITROSCOT NITROSCOT NITROLINGUAL RETARD CORNIT CORNIT CARDNIT CARDNIT GLYTRIN NITROCINE REFCOF REFCOF REFCOF CARA-GLYTRIN GLYRATE-SR GLYRATE-SR GLYCON-N GLYCON-N NIGLYS NIGLYS NITRIL NITROSID WEBSER

Dose: 0.5 to 1 mg
Single Dose: 0.75 (0.75)
Frequency: As recommended.
Route: Sublingual
Instructions: As required _x000D_glyceryl trinitrate can be repeated every 3 minutes untill pain relieves.

Dose:
Single Dose:
Frequency:
Route:
Instructions: Not recommended in this age group

Dose:
Single Dose:
Frequency:
Route:
Instructions: Not recommended in this age group

Glyceryl Trinitrate also known as Trinitrin, Trinitrin, Trinitrin, Trinitrin, Trinitrin. . It is of Synthetic origin and belongs to Nitropropane. It belongs to EDRF (NO) agonist pharmacological group on the basis of mechanism of action and also classified in Antianginal Agents and Vasodilators pharmacological group.The Molecular Weight of Glyceryl Trinitrate is 227.10.

Glyceryl Trinitrate is contraindicated in conditions like Glucoma,Hypovolaemia,Cardiac temponade,Cardiomyopathy,Cor pulmonale,Mitral valve prolapse,Raised intracranial pressure.

The severe or irreversible adverse effects of Glyceryl Trinitrate, which give rise to further complications include Tachycardia, Bradycardia, Collapse.The signs and symptoms that are produced after the acute overdosage of Glyceryl Trinitrate include Hypotension, Flushing, Tachycardia, Coma, Palpitations, Metabolic acidosis, Headache, Cardiovascular collapse, Syncope, Neurologic deficit, Methemoglobinemia, Increased intracranial pressure, Hypoxia, Cyanosis.The symptomatic adverse reactions produced by Glyceryl Trinitrate are more or less tolerable and if they become severe, they can be treated symptomatically, these include Weakness, Dizziness, Headache, Nausea, Vomiting, Restlessness, Palpitation, Abdominal pain, VertigoX, Urinary incontinence, Contact dermatitis, Syncope, Fecal incontinence, Orthostatic hypotension, dizziness.

'Glyceryl Trinitrate is primarily indicated in conditions like Anal fissure, Angina pectoris, Cardiac failure, Cardiopulmonary oedema, Long-term treatment of healed reflux oesophagitis, Moderate to severe reflux oesophagitis, Myocardial infarction, Oesophageal spasm, Oesophageal spasm, Postoperative hypertension, Prinzmetal''s angina, Prophylaxis of angina, Unstable angina.'

Glyceryl Trinitrate is known to interact with other drugs, the details of drug interactions is as follows:DrugDetailsSeverityOnsetManagementAlcoholAlprostadilEnhanced hypotensive effects when alprostadil given with Nitrates (e.g Glyceryl trinitrate).ApomorphineSublingual apomorphine enhances hypotensive effecs of nitrates.AspirinAtropine (Sulphate)Ergotamine (Tartrate)glyceryl trinitrate increase oral bioavailibilty and plasma concentration of dihydroergotamine in patients with orthostatic hypotensionHeparin (Na) and Heparin (Cl)Imipramine (HCl)Quinagolide (HCl)Rauwolfia ReserpineReserpine These interactions are sometimes beneficial and sometimes may pose threats to life. Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.

False decrease in serum cholestrol by Zlotkis-Zak color reaction technique. Increased urinary conc. of catecholamines and their metabolites.

Drug should not be given to Paediatrics, Pregnant Mothers, patients suffering from Kidney dysfunction, patients suffering from Liver Malfunction, Geriatrics, and Neonates.If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.

Store Between 15°C-30°C.

Excessive use of glyceryl trinitrate may cause headache, so reduce the dose & use analgesics (painkiller). Patients with gastrointestinal (GI) hypermotality or malabsorption syndrome should take oral or sublingual sustained release capsules rather than tablets. In terminating treatment of angina, gradually reduced the dose in order to avoid withdrawal reactions. It should not be used in patients with severe hypotension, hypovolaemia marked anemia, heart failure due to obstruction, raised intracranial pressure or angle closure glaucoma. It should be used with caution in patients with impaired kidney or liver function or hypothyroidism.Hypothermia, cereberovascular disease disease lung disease, lung desease or cor pulmonole pregnancy,lactation mitral value prolopre syncope.