GLIZID-5 GLIPASE GLIBENSE MINIDIAB MINIDIAB AF MINIDIAB AF MINIDIAB AF GLEEZID

Dose: 2.5 to 5 mg
Single Dose: 3.8 (3.75)
Frequency: 24 hourly
Route: PO
Instructions: Max dose 40 mg. Dose >15 mg given in 2 divided doses.

Dose:
Single Dose:
Frequency:
Route:
Instructions: Not recommended in this age group

Dose:
Single Dose:
Frequency:
Route:
Instructions: Not recommended in this age group

Glipizide also known as Glipizida, Glipizida. . It is of Synthetic origin and belongs to Sulphonyl Urea. It belongs to Potassium Channel (ATP sensitive) antagonist pharmacological group on the basis of mechanism of action and also classified in Antidiabetic Agent, Sulfonylurea pharmacological group.The Molecular Weight of Glipizide is 445.00. Its pKa is 5.9.

Glipizide is contraindicated in conditions like Thyroid disease,Impaired hepatic function,Iddm,Impaired renal function.

Glipizide produces potentially life-threatening effects which include Agranulocytosis, Thrombocytopenia, Hypoglycemia, Hypoglycemia, Hypoglycemia, Toxic hepatitis, Gastroenteritis. which are responsible for the discontinuation of Glipizide therapy.The symptomatic adverse reactions produced by Glipizide are more or less tolerable and if they become severe, they can be treated symptomatically, these include Allergic skin reactions.

Glipizide is primarily indicated in conditions like NIDDM, Non-insulin dependent diabetes mellitus, Type II diabetes mellitus.

Glipizide is known to interact with other drugs, the details of drug interactions is as follows:DrugDetailsSeverityOnsetManagementAlcoholAspirinHypoglycemic effect of glipizide may be potentiated by aspirin by stimiulating insulin secretion.ModerateClosely monitor the development of hypoglycaemia.Salicylic AcidSulphamethizoleGlipizide may be displaced from protein binding sites or their metabolism may be inhibited by some sulfonamides, resulting in increased or prolonged effects or toxicity.Dosage adjustments may be necessary during and after sulfonamide therapyTrimethoprim These interactions are sometimes beneficial and sometimes may pose threats to life. Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.

Monitoring of blood and urine glucose

Drug should not be given to Paediatrics, Pregnant Mothers, Geriatrics, and Neonates.If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.

Tab Store in a well closed container, Below 40°C.

Glipizide should be used with caution in patients with high blood pressure or liver or kidney disease. Avoid alcohol while taking this medication. Photosensitization may occur, so wear protective clothing and a sunscreen. It should be used with caution during pregnancy or lactation.