Alcuronium (Cl)

Alcuronium (Cl) is a competitive or non-depolarizing neuromuscular blocking agent. Alcuronium (Cl) is a synthetic derivative of the curare alkaloid Toxiferine. Alcuronium (Cl) is used to provide muscle relaxation in general anaesthesia (loss of conciousness) for surgical procedures.it has an intermediate onset and duration of action.

Brands
Adult Dose
Dose: 0.2 to 0.3 mg/kg
Single Dose: 0.25 (0.25)
Frequency: As recommended.
Route: IV
Instructions: As Required
Neonatal
Dose: 0.13 to 0.2 mg/Kg
Single Dose: 0.16 (0.165)
Frequency: As recommended.
Route: Intra Venous
Instructions: As Required
Paedriatic
Dose: 0.13 to 0.2 mg/Kg
Single Dose: 0.16 (0.165)
Frequency: As recommended.
Route: Intra Venous
Instructions: As Required
Characteristics
Alcuronium (Cl) also known as Allnortoxiferin Chloride. . It is of Synthetic origin and belongs to Nortoxiferinium. It belongs to Cholinergic nicotinic antagonist pharmacological group on the basis of mechanism of action and also classified in Muscle Relaxants pharmacological group.The Molecular Weight of Alcuronium (Cl) is 827.90.
Contraindications
Alcuronium (Cl) is contraindicated in conditions like Hypersensitivity.
Effects
Alcuronium (Cl) produces potentially life-threatening effects which include Anaphylactoid reactions, Hypotension, Cardiac Arrest, Cardiac arrest, Bronchospasm, Bronchospasm. which are responsible for the discontinuation of Alcuronium (Cl) therapy.The signs and symptoms that are produced after the acute overdosage of Alcuronium (Cl) include Prolonged respiratory & muscular paralysis.The symptomatic adverse reactions produced by Alcuronium (Cl) are more or less tolerable and if they become severe, they can be treated symptomatically, these include Skin reactions, GI symptoms, Increase in heart rate.
Indications
Alcuronium (Cl) is primarily indicated in conditions like Adjunct to anesthesia, Neuromuscular blockade.
Interactions
Alcuronium (Cl) is known to interact with other drugs, the details of drug interactions is as follows:DrugDetailsSeverityOnsetManagementBendrofluazideEnfluraneHalothaneHydroflumethiazideLignocaineLincomycin (HCl)PenicillaminePhenytoin (Na)Polymyxin B (Sulphate)Procainamide (HCl)QuinidineVerapamil (HCl) These interactions are sometimes beneficial and sometimes may pose threats to life. Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.
Interfrence
Risks
Drug should not be given to Pregnant Mothers, and patients suffering from Kidney dysfunction.If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.
Storage
IV Inj Store at room temperature. Protect from Sunlight.
Warnings
Alcuronium should be used with caution in patients with impaired renal function or during pregnancy.
Back to List

Any information that appears on this website page is provided for the purpose of general information. This website has been compiled in good faith by HMIS.Online. However, no guarantee is made as to the completeness, validity or accuracy of the information it contains.