Glibornuride

Glibornuride is oral hypoglycemic agent. Glibornuride is used to reduce the blood sugar level in the treatment of type 2 diabetes mellitus.


Brands
Adult Dose
Dose: 0.357 to 0.714 mg/kg
Single Dose: 0.54 (0.5355)
Frequency: 24 hourly
Route: PO
Instructions: -
Neonatal
Dose:
Single Dose:
Frequency:
Route:
Instructions: Not recommended in this age group
Paedriatic
Dose:
Single Dose:
Frequency:
Route:
Instructions: Not recommended in this age group
Characteristics
. It is of Synthetic origin and belongs to Sulphonylurea. It belongs to Potassium Channel (ATP sensitive) antagonist pharmacological group on the basis of mechanism of action and also classified in Antidiabetic Agent, Sulfonylurea pharmacological group.The Molecular Weight of Glibornuride is 366.50. Its pKa is 4.7.
Contraindications
Glibornuride is contraindicated in conditions like Renal diseases,Hepatic disease,Iddm,Diabetic coma.
Effects
Glibornuride produces potentially life-threatening effects which include Hypoglycemia, Hypoglycemia, Hypoglycemia. which are responsible for the discontinuation of Glibornuride therapy.The signs and symptoms that are produced after the acute overdosage of Glibornuride include Coma, Drowsiness, Confusion, Hypoglycemia, Sweating, Restlessness, Hunger, Trembling.The symptomatic adverse reactions produced by Glibornuride are more or less tolerable and if they become severe, they can be treated symptomatically, these include Nausea, Confusion, SweatingX, Confusion.
Indications
Glibornuride is primarily indicated in conditions like Type II diabetes mellitus.
Interactions
No data regarding the interactions of Glibornuride was found.
Interfrence
Altered liver euzyme valueNo effects on blood levels
Risks
Drug should not be given to Paediatrics, Pregnant Mothers, patients suffering from Kidney dysfunction, patients suffering from Liver Malfunction, and Neonates.If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.
Storage
Warnings
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