Fructose

Fructose used as a carbohydrate nutrient. itused in patient requiring fluid replacement and caloric feeding.


Adult Dose
Dose: 5%
Single Dose: 5 (5)
Frequency: As recommended.
Route: IV Inf
Instructions: 500-1000 ml as required.
Neonatal
Paedriatic
Characteristics
Fructose also known as Fruit Sugar, Fruit Sugar. . It is of Natural origin and belongs to Carbohydrate. It belongs to Nutrients and Vitamins pharmacological group on the basis of mechanism of action and also classified in Parenteral Nutrition pharmacological group.The Molecular Weight of Fructose is 180.20. It is weakly acidic drug, 5.05% solution of the drug is isotonic and Its pKa is 12.
Contraindications
Fructose is contraindicated in conditions like Liver diseases,Erratic fructose metabolism disease,Lactic acidosis,Methanol poisoning.
Effects
The severe or irreversible adverse effects of Fructose, which give rise to further complications include Hyperuricemia, Lactic acidosis.Fructose produces potentially life-threatening effects which include Blood lactate increase. which are responsible for the discontinuation of Fructose therapy.The signs and symptoms that are produced after the acute overdosage of Fructose include Diuresis, Hyperosmolarity.The symptomatic adverse reactions produced by Fructose are more or less tolerable and if they become severe, they can be treated symptomatically, these include Flatulence, Diarrhea, Abdominal pain, Sweating, Facial flushing, Hyperuricemia.
Indications
Fructose is primarily indicated in conditions like Nausea and vomiting, Parenteral nutrition.
Interactions
No data regarding the interactions of Fructose was found.
Interfrence
Serum test for Creatinine and Glucose Urine test for Creatine, Corticosteroids and metabolites, oestrogens and sugar
Risks
Drug should not be given to Pregnant Mothers, and patients suffering from Liver Malfunction.If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.
Storage
IV Inj
Warnings
Fructose should be used with caution in patients with known subclinical diabetes mellitus. It should be given with extreme caution to patients with impaired kidney function or severe liver damage. Should not be given to hereditary fructose intolerance.
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