RUMAGESIC RUMAGESIC OCUFEN MOBEZ OLGON ORAGESIC FROBEN FROBEN FROBEN FROBEN FENY JASIC ARTHROFEN FEN-100 RUBINOL ENDOL ENDOL EYEFLOX ANSAID PANSOL SYNALGO OPTOFEN FRODON SANID FLURBIN FLURBIN FLURITAB F-100 INOVAN INOVAN FBI FBI RELEPAN ROBIGESIC FLURGEM URBICID ADWIN FROBAFEN BIPROTEC FRUGESIC FLURIP FLURIP PANSAID PARAD BIPROFIN BIPROFIN NEO TRIAD NAPLUR BRO-Z SYRO NU-FLURBROFEN LUBIFEN FLUROFEN VELSAID FYSID HAFSAD LORBI FLUBI FLUR RAKAPROFEN ANAF BRUFOZ DOL MAGIFEN RANGAFEN RANGAFEN INFLAMATIX ANORCID FABOFEN OPTIPROFEN RASBID RIBOPROFEN PAINCID DISPERSEN SISKAT FLIP DANSAID FLUORAL BIPROGESIC ASKOSAID GLOFEN KOLZIN FLURFIN GETNOV ELIENT ULTIFEN FLASIC FLASIC FLAMTAB FLAMTAB PAROFEN PAROFEN DULPRO FLUSAID FLURSAID FLURBIMAK URBOFEN URBOFEN ZITIS EDGE FB-SAID FLURBIZAN FLURBIZAN FLURIDOL FLURITAB-100 FROGESIC HEALSED IB-PROOF NEFRO TAPROFEN RELAXOFEN RELAXOFEN RELAXOFEN VIO FEN VIO FEN VIOSAID RUBIO VOBIFEN TENCID BIAKE FLURWOOD FLURBIADVAN FERRYFEN FLOREFEN PICTOR PICTOR FLOG SWAPROFEN SWAPROFEN BALP DENTIFEN DOLORID FLUROFEN PRO-F PRO-F URBEN BENPROFEN FLORIP FLORIWEL FLORIWEL FLURWIN FLURWIN FLUWITT FUFIT SKEL FEN FLURLE INSTAGESIC MARIFEN Q-FUR ARBIPROFEN EXFLAM FABRUL FENPRO FENPRO HARISID PURICAP STREFEN FLURBAC TORNIL ENFLAM FLURANT OSTIFLUR FEBAGYL FLURUN SAPID

Dose: 0.03%
Single Dose: 0.03 (0.03)
Frequency: As recommended.
Route: Ophthalmic
Instructions: As Required.To be given as drops.

Dose:
Single Dose:
Frequency:
Route:
Instructions: Not recommended in this age group

Dose: 3 mg/kg
Single Dose: 3 (3)
Frequency: 24 hourly
Route: Oral
Instructions: -

Flurbiprofen Sodium is the derivative of Flurbiprofen. It is of Synthetic origin and belongs to Propionic Acid. It belongs to Cyclo-oxygenase inhibitor pharmacological group on the basis of mechanism of action and also classified in Opthalmic Products and Propionic Acid pharmacological group.The Molecular Weight of Flurbiprofen is 244.30.

Flurbiprofen is contraindicated in conditions like Peptic ulcer,Ulcerative colitis,Bronchospasm.

Flurbiprofen produces potentially life-threatening effects which include Hemorrhage, Peptic ulceration, Perforation. which are responsible for the discontinuation of Flurbiprofen therapy.The symptomatic adverse reactions produced by Flurbiprofen are more or less tolerable and if they become severe, they can be treated symptomatically, these include Dizziness, Tinnitus, GI reactions, Blurred vision, Peripheral edema, Deafness, Cutaneous vasculitis, Epidermal necrosis, Exfoliative dermatitis, Lichinoid eruptions.

Flurbiprofen is primarily indicated in conditions like Adjunct in GI-disorders, Ankylosing spondylitis, Dysmenorrhoea, Gout, Juvenile chronic arthritis, Mild to moderate pain, Musculoskeletal disorders, Nausea and vomiting (palliative care), Non-steroidal anti-inflammatory drugs (NSAID), Osteoarthritis, Pain, Post operative analgesia, Rheumatoid arthritis.

Flurbiprofen is known to interact with other drugs, the details of drug interactions is as follows:DrugDetailsSeverityOnsetManagementAlcoholAspirinAspirin decreases the plasma concentration of flurbiprofen. Aspirin may displace flurbiprofen from plasma protein binding site results in increased concentration of unbound, or free, drug available for clearence.During concomitant therapy, patient should take medication with food.AtenololAntihypertensive effect of Atenolol may decrease if use with Flurbiprofen sodium.Cyclosporin ARisk of nephrotoxicity increases if given with cyclosporin.Frusemide or FurosemideFlurbiprofen may diminish the diuretic effect of Furosemide.ModerateMonitor for decreased therapeutic effects of Furosemide if a nonsteroidal anti-inflammatory agent (NSAID) is initiated/dose increased, or increased effects if an NSAID is discontinued/dose decreased. Consider using an NSAID that holds a lesser potential for interacting with Furosemide (eg, diflunisal, flurbiprofen, ketoprofen, and ketorolac). Patients with heart failure may be more sensitive to alterations in fluid balance, in which case consideration should be given to avoiding the concomitant use of NSAIDs and Furosemide. Cirrhotic patients with ascites may also be at increased risk.LacosamideMethotrexateFlurbiprofen increases the plasma concentration of methotrexate by interfering with renal elimination results in increased toxicity and pharmacological effects.MajorClosely monitor for signs of bone marrow suppression and nephrotoxicity. Avoid any other over-the-counter NSAID product.Phenylbutazone Phenytoin (Na)TorasemideFlurbiprofen, a strong CYP2C9 inhibitor, may increase the serum concentration of Torasemide, a CYP2C9 substrate, by decreasing Torasemide metabolism and clearance. Consider alternate therapy or monitor for changes in the therapeutic and adverse effects of Torasemide if Flurbiprofen is initiated, discontinued or dose changed.VORICONAZOLEFlurbiprofen may increase the serum concentration of voriconazole by decreasing its metabolism. Monitor for changes in the therapeutic and adverse effects of voriconazole if flurbiprofen is initiated, discontinued or dose changed.Zidovudine These interactions are sometimes beneficial and sometimes may pose threats to life. Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.

Abnormal LFTs Complete blood cell count

Drug should not be given to Pregnant Mothers, and Neonates.If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.

Eye Drops Store Below 40°C. Do not Freeze. Protect from Sunlight and Moisture. Tab Store Below 40°C. Protect from Sunlight and Moisture.

Flurbiprofen should be used with caution in patients with history especially of any liver or kidney disease, blood disorders, ulcers, heart disease, alcohol use, high blood pressure, eye disease or allergies, especially drug allergies. It should be used with caution when performing tasks requiring alertness. Limit alcohol intake as it may intensify the drowsiness effect of this medication and make stomach or intestines more likely to bleed. Caution is advised when this drug is used in the elderly. This medication should be used during pregnancy or lactation only if clearly needed. Use of this drug during the last 6 months of pregnancy is not recommended.