BACTOXYL BACTOXYL BIFLOCIN BIFLOCIN BIFLOCIN FLOMOXIN FLOMOXIN F-CLOX F-CLOX FLUCOMOX FLUCOMOX TWIN TWIN A-FLOX A-FLOX A-FLOX A-FLOX DELFLOX DELFLOX FLOXAPEN FLOXAPEN FLOXAPEN FLOXAPEN AMFLOX AMFLOX CO-FLUX CO-FLUX XUNIZA XUNIZA FLUMOXIPEN FLUMOXIPEN FLUMOXIPEN

Dose: 125 to 250 mg/kg
Single Dose: 190 (187.5)
Frequency: 6 hourly
Route: Inhalation
Instructions: Desolved in 3 mL of sterile water and inhaled by nebuliser.

Dose: 7.81 mg/kg
Single Dose: 7.8 (7.81)
Frequency: 6 hourly
Route: Oral
Instructions:

Dose: 0 to 6.25 mg
Single Dose: 3.1 (3.125)
Frequency: 4 hourly
Route: Oral
Instructions: Under 2 Years

Floxacillin (Na) also known as Flucloxacillin, Flucloxacillin, Flucloxacillin. . It is of Semi Synthetic origin and belongs to Isoxazolylpenicillin. It belongs to Peptidoglycan synthesis inhibitor pharmacological group on the basis of mechanism of action and also classified in Antibiotics pharmacological group.The Molecular Weight of Floxacillin (Na) is 493.90. It is weakly acidic drug and Its pKa is 2.7.

Floxacillin (Na)

The severe or irreversible adverse effects of Floxacillin (Na), which give rise to further complications include Cholestatic jaundice, Blood dyscrasias, Neutropenia, Cholestasis, Nephritis.Floxacillin (Na) produces potentially life-threatening effects which include Pseudomembranous colitis, Anaphylaxis. which are responsible for the discontinuation of Floxacillin (Na) therapy.The signs and symptoms that are produced after the acute overdosage of Floxacillin (Na) include Nausea, Vomiting, Diarrhea, Abdominal discomfort.The symptomatic adverse reactions produced by Floxacillin (Na) are more or less tolerable and if they become severe, they can be treated symptomatically, these include GI adverse effects, Phlebitis.

Floxacillin (Na) is primarily indicated in conditions like Bacterial infections, Cellulitis, Endocarditis, Food allergy, Impetigo, Meningitis, Osteomyelitis, Otitis externa, Respiratory tract infections, Reversal of non-depolarisisng neuromuscular blockade, Septicaemia, Skin infections, Small cell carcinoma, Soft tissue infections, Staphylococcal enterocolitis, UTI, and can also be given in adjunctive therapy as an alternative drug of choice in Cardiothoracic surgery, Orthopaedic surgery.

No data regarding the interactions of Floxacillin (Na) was found.

HPLC Assay for Baclofen in Plasma Guthrie screening Test for phenylketonuria

Drug should not be given to Pregnant Mothers, and patients suffering from Kidney dysfunction.If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.

Caps, Powder for Inj, Powder for Susp Protect from Moisture. Reconstituted Inj Store in refrigerator. Use within 24 hrs if kept at room temperature. Reconstituted Syrup Store in refrigerator. Use within 14 days if kept at room temperature.

Before initiating therapy with flucloxacillin, careful inquiry should be made concerning previous hypersensitivity reactions to beta-lactams. Cross-sensitivity between penicillins and cephalosporins is well documented. Special caution is essential in the newborn because of the risk of hyperbilirubinemia. Studies have shown that, at high dose following parenteral administration, flucloxacillin can displace bilirubin from plasma protein binding sites, and may therefore predispose to kernicterus in a jaundiced baby. In addition, special caution is essential in the newborn because of the potential for high serum levels of flucloxacillin due to a reduced rate of renal excretion.