DUROGESIC DUROGESIC FENTYL FENTYL FENTRA

Dose: 0.714 to 1.428 ug/kg
Single Dose: 1.1 (1.071)
Frequency: As recommended.
Route: IM
Instructions: 30-60 Min before anaesthesia

Dose: Not safe under 2 Yrs of children
Single Dose:
Frequency:
Route:
Instructions:

Dose: 1.7 to 3.3 ug/kg
Single Dose: 2.5 (2.5)
Frequency: As recommended.
Route: Intra Muscular
Instructions: For Induction and Maintenance ,not safe below 2 Yrs.

Fentanyl (Citrate) also known as Phentonyl, Phentonyl, Phentonyl. . It is of Synthetic origin and belongs to Opioid. It belongs to OPIATE agonist pharmacological group on the basis of mechanism of action and also classified in Analgesic pharmacological group.The Molecular Weight of Fentanyl (Citrate) is 528.60. Its pKa is 8.43.

Fentanyl (Citrate) is contraindicated in conditions like Hypovolaemia,Hypotension,Raised intracranial pressure,Respiratory insufficiency.

The severe or irreversible adverse effects of Fentanyl (Citrate), which give rise to further complications include Glottic closure.Fentanyl (Citrate) produces potentially life-threatening effects which include Respiratory depression. which are responsible for the discontinuation of Fentanyl (Citrate) therapy.The symptomatic adverse reactions produced by Fentanyl (Citrate) are more or less tolerable and if they become severe, they can be treated symptomatically, these include Urinary retensionX, Nausea and vomiting.

Fentanyl (Citrate) is primarily indicated in conditions like Analgesia during operation, enhancement of anaesthesia, Pain, and can also be given in adjunctive therapy as an alternative drug of choice in Anesthesia.

Fentanyl (Citrate) is known to interact with other drugs, the details of drug interactions is as follows:DrugDetailsSeverityOnsetManagementAlcoholAtracurium (Besylate)CyclizineDroperidolEtomidateMidazolamMoclobemideNalbuphine (HCl)NicardipineNitrous OxideSibutramineVecuronium (Br)Vecuronium (Br)VORICONAZOLEVoriconazole may increase the serum concentration of fentanyl by decreasing its metabolism.Monitor for changes in the therapeutic and adverse effects of fentanyl if voriconazole is initiated, discontinued or dose changed.Vortioxetineincreases the level of vortioxetinemonitor closely, use alternative These interactions are sometimes beneficial and sometimes may pose threats to life. Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.

Drug should not be given to Pregnant Mothers, and Neonates.If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.

Inj Store Below 40°C. Protect from Sunlight and Moisture. Lozenges Store in a well closed container, Below 40°C. Do not Freeze. Protect from Sunlight and Moisture.

Fentanyl should be used with caution in patients with central nervous system (CNS) depression, convulsive disorder, ulcerative colitis, fever, recent GI surgery, bradyarrhythmias, supraventricular tachycardia, pulmonary diseases. Patients should exercise caution while driving or performing tasks requiring alertness because it may produce drowsiness.