ETOMIDATE LIPURO

Dose: 20 mg
Single Dose: 20 (20)
Frequency: As recommended.
Route: Slow IV
Instructions: As Required

Dose: 0.3 mg/kg
Single Dose: 0.3 (0.3)
Frequency: As recommended.
Route: Slow IV
Instructions: As Required

. It is of Synthetic origin and belongs to Phenylethyl Imidazole. It belongs to Chloride Channel Potentiater (GABA operated) pharmacological group on the basis of mechanism of action and also classified in General Anesthetics pharmacological group.The Molecular Weight of Etomidate is 244.30. Its pKa is 4.1.

Etomidate is contraindicated in conditions like Epilepsy,Porphyrias,Adrenocortical insufficiency.

The severe or irreversible adverse effects of Etomidate, which give rise to further complications include Cortisol synthesis inhibition.Etomidate produces potentially life-threatening effects which include Reduction in serum cortisol. which are responsible for the discontinuation of Etomidate therapy.The signs and symptoms that are produced after the acute overdosage of Etomidate include Rapid fall in BP.The symptomatic adverse reactions produced by Etomidate are more or less tolerable and if they become severe, they can be treated symptomatically, these include Nausea, Vomiting, Involuntry muscle movements, Pain at injection site.

Etomidate is primarily indicated in conditions like Anaesthesia induction in cardiovascular patients.

Etomidate is known to interact with other drugs, the details of drug interactions is as follows:DrugDetailsSeverityOnsetManagementAtropine (Sulphate)EnfluraneFentanyl (Citrate)HalothanePapaveretumPethidine (HCl)Promethazine (HCl)Vecuronium (Br)Verapamil (HCl) These interactions are sometimes beneficial and sometimes may pose threats to life. Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.

Drug should not be given to Pregnant Mothers, and patients suffering from Liver Malfunction.If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.

Inj Store at room temperature. Do not Freeze. Protect from Sunlight.

Patients should observe caution while driving or performing other tasks requiring alertness, because may cause drowsiness. Patients with chronic disease such as diabetes or hypertension may require adjustment to their therapy before anesthesia. Anesthetics should be given with caution in patients with cardiac, respiratory, renal or hepatic impairment.