Drostanolone (Propionate)

Drostanolone (Propionate) was formerly used in treatment of advanced breast cancer in post-menopausal females.


Brands
Adult Dose
Dose: 1.429 mg/kg
Single Dose: 1.4 (1.429)
Frequency: As recommended.
Route: IM
Instructions: Thrice a Week
Neonatal
Paedriatic
Characteristics
. It is of Synthetic origin and belongs to Steroid. It belongs to Aldosterone agonist pharmacological group on the basis of mechanism of action and also classified in Hormones and Anabolic Steroid pharmacological group.The Molecular Weight of Drostanolone (Propionate) is 360.50. Its pKa is not relevant.
Contraindications
Drostanolone (Propionate) is contraindicated in conditions like Hepatic disease,Carcinoma of male breast,Cardiac disease,Prostate cancer.
Effects
The severe or irreversible adverse effects of Drostanolone (Propionate), which give rise to further complications include Hoarseness, Deepening of voice.The symptomatic adverse reactions produced by Drostanolone (Propionate) are more or less tolerable and if they become severe, they can be treated symptomatically, these include Acne, Virilization, Coarser skin, Facial hair, Clitoromegaly.
Indications
Drostanolone (Propionate) is primarily indicated in conditions like Metastatic carcinoma of breast.
Interactions
No data regarding the interactions of Drostanolone (Propionate) was found.
Interfrence
Risks
Drug should not be given to Paediatrics, Pregnant Mothers, Cardiac / Hypertensive Patients, patients suffering from Kidney dysfunction, and Neonates.If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.
Storage
Warnings
Patients should be instructed to report any of the following: nausea, vomiting, changes in skin color, and ankle swelling. Males should be instructed to report too frequent or persistent erections of the penis and females any hoarseness, acne, changes in menstrual periods or increase in facial hair.
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