DOXYN DOXYN APDOXY APDOXY FENSEPTYL MONODOX MONODOX DOXYCYCLINE HYCLATE OROCYCLINE ACNEDOX ADOXA DOXYCLATE DOXYDOS DOXYCYCLINE DOXIT DC-CAP CONTIMYCIN DROSS DOXCIL DOXCIL DOXCIL ETHIDOX EPIDOX WELLCODOX DOXICAP CAPSIDON CAPSIDON ARANDOX ETIDOXINE MEGADOX REMYCIN REMYCIN DOXYMYCIN KAROXYN DOXIKEY VIBRADOXIN VIBRADOXIN JAWAMYCIN JAWAMYCIN NOVOCYCLINE ALPODOX ALPODOX ISIS ISIS NEUTROCYN DOXYTAB DOTUR EXMYCIN VIBREX VIBREX SUPRAMYCIN ARBEV ARBEV CORODOX VIBRAMYCIN VIBRAMYCIN VIBRAMYCIN PARKEDOX DOXYLIN DOLCYCLINE DEKOMYCIN RAPIDOX RAPIDOX CECOX NORDOX DOXYCYCLINE ROGODOX BSADOX MAXIBIOTIC MAXIBIOTIC SIZADOX DEMOXIN BIBRACIN BIBRACIN RIDOX DOXYCYCLINE VIBRATAB DOXYCYCLINE KORCIN SLOCYCLINE DOXYREX DOXYCYCLINE DOXYLIDE DOXYLIDE ARDOX VIBASAN VIBASAN NOVODOX CEDOX MB-DOX LIBRACIN VOXIN OCECYCLINE XYLIN XYLIN XYLIN INFADOX AREDOX AREDOX DOXYLINE DOXYGEN D-CLIN DUMARD DUMARD DOXYMED PANDOX PANDOX DOXYHEIM DOXYHEIM SAVIMYCIN LODOFAM DOXY-A AKNIDOX DOXER DOXER DOXCID DANCILIN U-SODOX M-DOX DOXYSEARCH ALDOXY ALDOXY DECLOCINE DECLOCINE RODOX DUKE LEXIDOX LEXIDOX JOXY KODEX DOCLINE DOCLINE DOXYLEY DOXYLEY CHERDOX CHERDOX DOXINOM DOXINOM MERIDOX HYCLOFAT DOXYBACT DORYXBRO

Dose: 100 mg
Single Dose: 100 (100)
Frequency: 24 hourly
Route: PO
Instructions: Maintenance, As Required

Dose:
Single Dose:
Frequency:
Route:
Instructions: Not recommended in this age group

Dose:
Single Dose:
Frequency:
Route:
Instructions: Not recommended in this age group

Doxycycline HCl, Doxycycline HCl are the derivatives of Doxycycline. It is of Semi Synthetic origin and belongs to Tetracycline. It belongs to Antibacterial (Proetin synthesis inhibitor) pharmacological group on the basis of mechanism of action and also classified in Antibiotic, Tetracycline Derivative pharmacological group.The Molecular Weight of Doxycycline is 462.00. It is weakly alkaline drug and Its pKa is 3.4, 7.7, 9.7.

Doxycycline is contraindicated in conditions like Systemic lupus erythematosus,Hypersensitivity.

The severe or irreversible adverse effects of Doxycycline, which give rise to further complications include Staining of developing teeth, Hypoplasia of enamel.Doxycycline produces potentially life-threatening effects which include Pseudomembranous colitis, Anaphylaxis, Liver damage. which are responsible for the discontinuation of Doxycycline therapy.The signs and symptoms that are produced after the acute overdosage of Doxycycline include GI disturbances.The symptomatic adverse reactions produced by Doxycycline are more or less tolerable and if they become severe, they can be treated symptomatically, these include Nausea, Anorexia, Skin reactions, Skin rashes, Maculopapular rash, Urticaria, Vaginitis, Photosensitivity, Glossitis, StomatitisX, Hemolytic anemia, Dysphagia, Erythematous rash, Pericarditis, Exfoliative dermatitis, GI disturbance, Anaphylactoid purpura.

Doxycycline is primarily indicated in conditions like Acne vulgaris, Anthrax, Breast cancer, Chronic lymphocytic leukaemia, Genitourinary tract infections, GI infections, Heart failure, Malaria prophylaxis, Opthalmic infections, Plasmodium falciparum malaria, Pneumonia, Respiratory tract infections, Schizophrenia and other psychoses, Severe infections, Sinusitis, Soft tissue infections, To reduce degradation of pancreatic enzyme supplements, and can also be given in adjunctive therapy as an alternative drug of choice in Adjunct in the treatment of P. Falciparum malaria, Adult growth hormone deficiency, Moderate to severe rheumatoid arthritis, Rosacea.

Doxycycline is known to interact with other drugs, the details of drug interactions is as follows:DrugDetailsSeverityOnsetManagementAlcoholCarbamazepineCarbamazepine accelerates metabolism of Doxycycline (reduced effect) and shortens the half life of doxycycline. Chlorpheniramine (Maleate)It increases effects of chlotpheniramine. as it is is a CYP3A4 inhibitorClavulanic AcidFosphenytoinGlymidineIron SaltsMagnesium Oxides and HydroxidesPhenobarbitonePhenobarbitonePhenytoin (Na)Phenytoin (Na)Riboflavin (Vitamin B2)Riboflavin interferes with the absorption and effectiveness of tetracyclines.RifampicinSodium AcetateAlkalinization of the urine may decrease the plasma concentration of some tetracyclines. The mechanism is not completely understood, but may involve increased renal elimination of tetracyclines when the urine becomes alkalinized. ModerateIf these drugs must be used together, an alternating dosing schedule is recommended (three to four hours apart).Sodium BicarbonateSodium PicosulphateShould not be use concurrently without doctors prescription. These interactions are sometimes beneficial and sometimes may pose threats to life. Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.

The rise in blood urea Elevations of SGPT and SGOT Interference with Urinary Urobilinogen Levels Rise in Eosinophil count

Drug should not be given to Paediatrics, Pregnant Mothers, and Neonates.If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.

Inj (reconstituted soln) Store . Protect from Sunlight. Oral Syrup or Susp Store at room temperature. Do not Freeze. Protect from Sunlight. Tab, Caps Store Below 40°C. Protect from Sunlight.

Doxycycline should be used with caution (if contains tartrazine) in patients with aspirin hypersensitivity, because it may cause allergic reactions (including bronchial asthma). Take appropriate measures if secondary infection occurs. Perform periodic laboratory evaluation of organ system (e.g. liver or kidney) in case of long term therapy.