VOMILUX VOMILUX EPODOM EPODOM ALMEDON ALMEDON ALMEDON PERILIUM PERILIUM PERILIUM DOMOTIN DOMOTIN DOMEL DOMEL DOLIRICIN DOLIRICIN NOMIT NOMIT FELIUM FELIUM PELTON-C PELTON-V PELTON-V PELTON PELTON PELTON PELTON D DONE DOMPEDONE DOMPEDONE STOMACOL STOMACOL ENTEVIGOR ENTEVIGOR ENTEVIGOR TYPERDON TYPERDON TYPERDON MOTILIUM MOTILIUM MOTILIUM-V DOMOZAT DOMOZAT VOMNIL VISDOM VISDOM DOMIPAR DOMIPAR PERICID MOTIL MOTIL MOTIL MOTIL PERID-M PERID PERID OTATONE OTATONE VOMSON NENDONE NENDONE NENDONE PROKIN NEOPERI NEOPERI PENTEX MOTIREG UNIDON-V UNIDON-V UNIDON UNIDON UNIDON PURIDON DEVOMET DOMPTILLIUM DOMPTILLIUM EMISET EMISET EMIDONE PERIDONE PERIDONE NV-NIL AVIFIX DOMINO DOME-ONE DOME-ONE MALDOM DOLIUM DOLIUM DOLIUM PEPTEZE PEPTEZE STOMEZE STOMEZE AKSOTIN GERIN GERIN SEVIDON-V RIDON SEVIDON APPDOM MILIUM-V MILIUM MILIUM DOMPTILIUM PERILL PERILL PERILL ZELIUM MAPRID STARDONE STARDONE ARDILIUM STAPERIDONE STAPERIDONE MEDIDOME EROLIUM NOSILEX V-LUM MUTIL VOMITIL NAUDON MOTILITE EMORIP DOMPYRAX DOMPYRAX DOMPYRAX DONALID AL-PRIDONE AL-PRIDONE DOMPRO OPTILIUM F-DOM MEBZOLE OMPERIN OMPERIN CINARIUM DO-GE DOMCIN EVDON V EVDON MOVEDON-V MOVEDON VOMIDONE-C QILIUM RAPIDON RESIDONE REIDON MOTICOL OLIDON OLIDON OLIDON OLIDON M RAZIM JPERIDON JPERIDON MEDIDONE VOMISTOP-C VOMISTOP MOTEDONE MOTEDONE PEPTIMAX-V ALBONE DOM-RETARD DOM-FASTR RAPIDONE RAPIDONE RAPIDONE GASTRILIUM VEDONE DOMOFIT DOMOFIT DOMOFIT DOMOFIT GASTROCURE GASTROCURE GASTROCURE KINETIC KINETIC MAKDONE-M MOPREL MOPREL MOPREL V MOLIUM MOLIUM DOMYCARE DOMILIUM DO ONE DO ONE DO ONE H-DONE H-DONE H-DONE DODON MOTIDIL GASTROKE GASTROKE GASTROKE DOMWIS DOMWIS PERISTAL EDOM EDOM CINPERI EMETUS EMETUS C-DOM AMBRILIUM AMBRILIUM RI-ONE RI-ONE V DOMMED-C DOMZINE DOMGEN MOPERIUM DOMID DOMID MAXTELIUM UNIPRID DOMEC SYDIDON VOMAX VOMAX ZOTRIUM ZOTRIUM DOMSAVE DYPIN-V DOMIDON EMOLIUM EMOLIUM

Dose: 10 to 20 mg
Single Dose: 15 (15)
Frequency: 6 hourly
Route: PO
Instructions: 15-30 minutes before meal. It can be used for maximum 12 weeks.

Dose: 0.2 to 0.4 mg/kg
Single Dose: 0.3 (0.3)
Frequency: 8 hourly
Route: Oral
Instructions: -

Dose: 250 to 0.4 ug/kg
Single Dose: 130 (125.2)
Frequency: 8 hourly
Route: Oral
Instructions: 15-30 minutes before meal. It can be used for maximum 12 weeks. To a total daily dose of 80mg.

. It is of Synthetic origin and belongs to Benzimidazolin. It belongs to Antiemetic/Antivertigo Agents pharmacological group.The Molecular Weight of Domperidone is 425.90. Its pKa is 7.9.

Domperidone is contraindicated in conditions like Allergy,Hepatic impairment,Serious resistant GI mycoses.

The severe or irreversible adverse effects of Domperidone, which give rise to further complications include Tardive dyskinesia, Parkinsonism, Extrapyramidal dystonic reactions.Domperidone produces potentially life-threatening effects which include Seizures, Dysrhythmias. which are responsible for the discontinuation of Domperidone therapy.The signs and symptoms that are produced after the acute overdosage of Domperidone include Convulsions, Coma, GI disturbances, Extrapyramidal effects.The symptomatic adverse reactions produced by Domperidone are more or less tolerable and if they become severe, they can be treated symptomatically, these include Thirst, Headache, Drowsiness, Diarrhea, Anxiety, Restlessness, Insomnia, Nervousness, Skin rashes, Dry mouth, Itching, Galactorrhea, Breast enlargement, Soreness, Hyperprolactinemia, nervousness, Reduced libido.

Domperidone is primarily indicated in conditions like Acute nausea and vomiting, Delayed gastric emptying, Dyspepsia, Functional dyspepsia, Gastric distension pain due to pressure on the stomach, Gastro-oesophageal reflux disease, Nausea and vomiting, Nausea and vomiting (chemotherapy induced), Nausea and vomiting (L-dopa induced), Non-ulcer dyspepsia, Reflux oesophagitis, and can also be given in adjunctive therapy as an alternative drug of choice in Cytotoxic chemotherapy, Heart burn, Lactation.

Domperidone is known to interact with other drugs, the details of drug interactions is as follows:DrugDetailsSeverityOnsetManagementApomorphineApomorphine antagonize the action of domperidone.Bromocriptine (Mesylate)Hypoprolactenamic effect of bromocriptine possibly antagonized by Domperidone. Bromocriptine (Mesylate)Hyperprolactanemia effect of Bromocriptine possibly antagonized by Domperidone.CabergolineHypoprolactinemic and antiparkinsonian effects of Cabergoline possibly antagonized by Domperidone. CinnarizineLisurideOxycodoneOxycodone antagonize the action of domperidone.PergolidePiribedilDomperidone reduce the effect of piribedil. These interactions are sometimes beneficial and sometimes may pose threats to life. Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.

Not well documented

Drug should not be given to Paediatrics, Pregnant Mothers, and Neonates.If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.

Tab Store Below 25°C.

Domperidone should be used with great caution if given intravaneously, because of the risk of arrhythmias, especially to patients predisposed to cardiac arrhythmias or hypokalaemia.