DOTREX DOBUJECT DOBUTREX DOBUTEL DOBEX BUTA DOBUTAMINE MYUNGMOON DOBUTAMINE MYUNGMOON DOBUTAMINE MYUNGMOON DOBUTAMINE MYUNGMOON DOBUTAMINE DOBUTAMED DOFLEX DUVIG DOBUTAMINE DOBUTAMINE CARA-DOBA

Dose: 175 to 2800 ug/min
Single Dose: 1500 (1487.5)
Frequency: As recommended.
Route: IV Inf
Instructions: As Required

Dose: 2.5 to 15 ug/kg.min
Single Dose: 8.8 (8.75)
Frequency: As recommended.
Route: Infusion
Instructions: As required

Dose: 2.15 to 20 mcg/kg/min
Single Dose: 11 (11.075)
Frequency: As recommended.
Route: as required
Instructions:

. It is of Synthetic origin and belongs to Catecholamine. It belongs to Alpha & Beta adrenergic agonist pharmacological group on the basis of mechanism of action and also classified in Drugs used in Shock and Adrenergic Agonist Agent pharmacological group.The Molecular Weight of Dobutamine (HCl) is 337.80. Its pKa is 9.5.

Dobutamine (HCl) is contraindicated in conditions like Obstructive cardiomyopathy,Constrictive pericarditis,Low cardiac filling pressure,Cardiac temponade,Ventricular arrhythmias.

The severe or irreversible adverse effects of Dobutamine (HCl), which give rise to further complications include Tissue necrosis.Dobutamine (HCl) produces potentially life-threatening effects which include Myocardial Ischemia, Tachycardia, Cardiac arrhythmias, Hypertension, Hypotension, Myocardial ischemia, Extravasation. which are responsible for the discontinuation of Dobutamine (HCl) therapy.The signs and symptoms that are produced after the acute overdosage of Dobutamine (HCl) include Hypertension, Peripheral vasoconstriction, Myocardial ischemia, Arrhythmias.The symptomatic adverse reactions produced by Dobutamine (HCl) are more or less tolerable and if they become severe, they can be treated symptomatically, these include Headache, Fatigue, Nausea, Vomiting, Palpitation, Non-specific chest pain, Breathlessness, Bronchospasm, Chest pain, Paresthesias, Reaction at injection site.

Dobutamine (HCl) is primarily indicated in conditions like Acid reflux disease (long-term management), Cardiac surgery, Cardiogenic shock, Cardiomyopathies, Heart failure, Hypotensive shock, Inotropic support in infarction, Septic shock, and can also be given in adjunctive therapy as an alternative drug of choice in Positive end expiratory pressure ventilation.

Dobutamine (HCl) is known to interact with other drugs, the details of drug interactions is as follows:DrugDetailsSeverityOnsetManagementDopamine (HCl)HalothaneMilrinone (Lactate)Phentolamine (Mesylate)PrazosinSodium Nitroprusside These interactions are sometimes beneficial and sometimes may pose threats to life. Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.

Reduction in serum potassium concentration

Drug should not be given to Paediatrics, Pregnant Mothers, and Neonates.If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.

Inj (reconstituted soln) Store at room temperature. Use within 24 hrs if kept at room temperature.

Correct hypovolemia with suitable volume expender before starting treatment with dobutamine in hypovolemic patients. Continuously monitor ECG, blood pressure and cardiac output. It should be used with extreme caution in patient with acute myocardial infarction. It is classified as pregnancy category C and should be avoided during pregnancy unless the potential benefit outweighs the isk to the fetus. Avoid in arrythmias, severe hypotension.